An official website of the United States government
The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Preview improvements coming to the PMC website in October 2024. Learn More or Try it out now .
Patricia farrugia.
* Michael G. DeGroote School of Medicine, the
† Division of Orthopaedic Surgery and the
‡ Departments of Surgery and
§ Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ont
There is an increasing familiarity with the principles of evidence-based medicine in the surgical community. As surgeons become more aware of the hierarchy of evidence, grades of recommendations and the principles of critical appraisal, they develop an increasing familiarity with research design. Surgeons and clinicians are looking more and more to the literature and clinical trials to guide their practice; as such, it is becoming a responsibility of the clinical research community to attempt to answer questions that are not only well thought out but also clinically relevant. The development of the research question, including a supportive hypothesis and objectives, is a necessary key step in producing clinically relevant results to be used in evidence-based practice. A well-defined and specific research question is more likely to help guide us in making decisions about study design and population and subsequently what data will be collected and analyzed. 1
In this article, we discuss important considerations in the development of a research question and hypothesis and in defining objectives for research. By the end of this article, the reader will be able to appreciate the significance of constructing a good research question and developing hypotheses and research objectives for the successful design of a research study. The following article is divided into 3 sections: research question, research hypothesis and research objectives.
Interest in a particular topic usually begins the research process, but it is the familiarity with the subject that helps define an appropriate research question for a study. 1 Questions then arise out of a perceived knowledge deficit within a subject area or field of study. 2 Indeed, Haynes suggests that it is important to know “where the boundary between current knowledge and ignorance lies.” 1 The challenge in developing an appropriate research question is in determining which clinical uncertainties could or should be studied and also rationalizing the need for their investigation.
Increasing one’s knowledge about the subject of interest can be accomplished in many ways. Appropriate methods include systematically searching the literature, in-depth interviews and focus groups with patients (and proxies) and interviews with experts in the field. In addition, awareness of current trends and technological advances can assist with the development of research questions. 2 It is imperative to understand what has been studied about a topic to date in order to further the knowledge that has been previously gathered on a topic. Indeed, some granting institutions (e.g., Canadian Institute for Health Research) encourage applicants to conduct a systematic review of the available evidence if a recent review does not already exist and preferably a pilot or feasibility study before applying for a grant for a full trial.
In-depth knowledge about a subject may generate a number of questions. It then becomes necessary to ask whether these questions can be answered through one study or if more than one study needed. 1 Additional research questions can be developed, but several basic principles should be taken into consideration. 1 All questions, primary and secondary, should be developed at the beginning and planning stages of a study. Any additional questions should never compromise the primary question because it is the primary research question that forms the basis of the hypothesis and study objectives. It must be kept in mind that within the scope of one study, the presence of a number of research questions will affect and potentially increase the complexity of both the study design and subsequent statistical analyses, not to mention the actual feasibility of answering every question. 1 A sensible strategy is to establish a single primary research question around which to focus the study plan. 3 In a study, the primary research question should be clearly stated at the end of the introduction of the grant proposal, and it usually specifies the population to be studied, the intervention to be implemented and other circumstantial factors. 4
Hulley and colleagues 2 have suggested the use of the FINER criteria in the development of a good research question ( Box 1 ). The FINER criteria highlight useful points that may increase the chances of developing a successful research project. A good research question should specify the population of interest, be of interest to the scientific community and potentially to the public, have clinical relevance and further current knowledge in the field (and of course be compliant with the standards of ethical boards and national research standards).
Feasible | ||
Interesting | ||
Novel | ||
Ethical | ||
Relevant |
Adapted with permission from Wolters Kluwer Health. 2
Whereas the FINER criteria outline the important aspects of the question in general, a useful format to use in the development of a specific research question is the PICO format — consider the population (P) of interest, the intervention (I) being studied, the comparison (C) group (or to what is the intervention being compared) and the outcome of interest (O). 3 , 5 , 6 Often timing (T) is added to PICO ( Box 2 ) — that is, “Over what time frame will the study take place?” 1 The PICOT approach helps generate a question that aids in constructing the framework of the study and subsequently in protocol development by alluding to the inclusion and exclusion criteria and identifying the groups of patients to be included. Knowing the specific population of interest, intervention (and comparator) and outcome of interest may also help the researcher identify an appropriate outcome measurement tool. 7 The more defined the population of interest, and thus the more stringent the inclusion and exclusion criteria, the greater the effect on the interpretation and subsequent applicability and generalizability of the research findings. 1 , 2 A restricted study population (and exclusion criteria) may limit bias and increase the internal validity of the study; however, this approach will limit external validity of the study and, thus, the generalizability of the findings to the practical clinical setting. Conversely, a broadly defined study population and inclusion criteria may be representative of practical clinical practice but may increase bias and reduce the internal validity of the study.
Population (patients) | ||
Intervention (for intervention studies only) | ||
Comparison group | ||
Outcome of interest | ||
Time |
A poorly devised research question may affect the choice of study design, potentially lead to futile situations and, thus, hamper the chance of determining anything of clinical significance, which will then affect the potential for publication. Without devoting appropriate resources to developing the research question, the quality of the study and subsequent results may be compromised. During the initial stages of any research study, it is therefore imperative to formulate a research question that is both clinically relevant and answerable.
The primary research question should be driven by the hypothesis rather than the data. 1 , 2 That is, the research question and hypothesis should be developed before the start of the study. This sounds intuitive; however, if we take, for example, a database of information, it is potentially possible to perform multiple statistical comparisons of groups within the database to find a statistically significant association. This could then lead one to work backward from the data and develop the “question.” This is counterintuitive to the process because the question is asked specifically to then find the answer, thus collecting data along the way (i.e., in a prospective manner). Multiple statistical testing of associations from data previously collected could potentially lead to spuriously positive findings of association through chance alone. 2 Therefore, a good hypothesis must be based on a good research question at the start of a trial and, indeed, drive data collection for the study.
The research or clinical hypothesis is developed from the research question and then the main elements of the study — sampling strategy, intervention (if applicable), comparison and outcome variables — are summarized in a form that establishes the basis for testing, statistical and ultimately clinical significance. 3 For example, in a research study comparing computer-assisted acetabular component insertion versus freehand acetabular component placement in patients in need of total hip arthroplasty, the experimental group would be computer-assisted insertion and the control/conventional group would be free-hand placement. The investigative team would first state a research hypothesis. This could be expressed as a single outcome (e.g., computer-assisted acetabular component placement leads to improved functional outcome) or potentially as a complex/composite outcome; that is, more than one outcome (e.g., computer-assisted acetabular component placement leads to both improved radiographic cup placement and improved functional outcome).
However, when formally testing statistical significance, the hypothesis should be stated as a “null” hypothesis. 2 The purpose of hypothesis testing is to make an inference about the population of interest on the basis of a random sample taken from that population. The null hypothesis for the preceding research hypothesis then would be that there is no difference in mean functional outcome between the computer-assisted insertion and free-hand placement techniques. After forming the null hypothesis, the researchers would form an alternate hypothesis stating the nature of the difference, if it should appear. The alternate hypothesis would be that there is a difference in mean functional outcome between these techniques. At the end of the study, the null hypothesis is then tested statistically. If the findings of the study are not statistically significant (i.e., there is no difference in functional outcome between the groups in a statistical sense), we cannot reject the null hypothesis, whereas if the findings were significant, we can reject the null hypothesis and accept the alternate hypothesis (i.e., there is a difference in mean functional outcome between the study groups), errors in testing notwithstanding. In other words, hypothesis testing confirms or refutes the statement that the observed findings did not occur by chance alone but rather occurred because there was a true difference in outcomes between these surgical procedures. The concept of statistical hypothesis testing is complex, and the details are beyond the scope of this article.
Another important concept inherent in hypothesis testing is whether the hypotheses will be 1-sided or 2-sided. A 2-sided hypothesis states that there is a difference between the experimental group and the control group, but it does not specify in advance the expected direction of the difference. For example, we asked whether there is there an improvement in outcomes with computer-assisted surgery or whether the outcomes worse with computer-assisted surgery. We presented a 2-sided test in the above example because we did not specify the direction of the difference. A 1-sided hypothesis states a specific direction (e.g., there is an improvement in outcomes with computer-assisted surgery). A 2-sided hypothesis should be used unless there is a good justification for using a 1-sided hypothesis. As Bland and Atlman 8 stated, “One-sided hypothesis testing should never be used as a device to make a conventionally nonsignificant difference significant.”
The research hypothesis should be stated at the beginning of the study to guide the objectives for research. Whereas the investigators may state the hypothesis as being 1-sided (there is an improvement with treatment), the study and investigators must adhere to the concept of clinical equipoise. According to this principle, a clinical (or surgical) trial is ethical only if the expert community is uncertain about the relative therapeutic merits of the experimental and control groups being evaluated. 9 It means there must exist an honest and professional disagreement among expert clinicians about the preferred treatment. 9
Designing a research hypothesis is supported by a good research question and will influence the type of research design for the study. Acting on the principles of appropriate hypothesis development, the study can then confidently proceed to the development of the research objective.
The primary objective should be coupled with the hypothesis of the study. Study objectives define the specific aims of the study and should be clearly stated in the introduction of the research protocol. 7 From our previous example and using the investigative hypothesis that there is a difference in functional outcomes between computer-assisted acetabular component placement and free-hand placement, the primary objective can be stated as follows: this study will compare the functional outcomes of computer-assisted acetabular component insertion versus free-hand placement in patients undergoing total hip arthroplasty. Note that the study objective is an active statement about how the study is going to answer the specific research question. Objectives can (and often do) state exactly which outcome measures are going to be used within their statements. They are important because they not only help guide the development of the protocol and design of study but also play a role in sample size calculations and determining the power of the study. 7 These concepts will be discussed in other articles in this series.
From the surgeon’s point of view, it is important for the study objectives to be focused on outcomes that are important to patients and clinically relevant. For example, the most methodologically sound randomized controlled trial comparing 2 techniques of distal radial fixation would have little or no clinical impact if the primary objective was to determine the effect of treatment A as compared to treatment B on intraoperative fluoroscopy time. However, if the objective was to determine the effect of treatment A as compared to treatment B on patient functional outcome at 1 year, this would have a much more significant impact on clinical decision-making. Second, more meaningful surgeon–patient discussions could ensue, incorporating patient values and preferences with the results from this study. 6 , 7 It is the precise objective and what the investigator is trying to measure that is of clinical relevance in the practical setting.
The following is an example from the literature about the relation between the research question, hypothesis and study objectives:
Study: Warden SJ, Metcalf BR, Kiss ZS, et al. Low-intensity pulsed ultrasound for chronic patellar tendinopathy: a randomized, double-blind, placebo-controlled trial. Rheumatology 2008;47:467–71.
Research question: How does low-intensity pulsed ultrasound (LIPUS) compare with a placebo device in managing the symptoms of skeletally mature patients with patellar tendinopathy?
Research hypothesis: Pain levels are reduced in patients who receive daily active-LIPUS (treatment) for 12 weeks compared with individuals who receive inactive-LIPUS (placebo).
Objective: To investigate the clinical efficacy of LIPUS in the management of patellar tendinopathy symptoms.
The development of the research question is the most important aspect of a research project. A research project can fail if the objectives and hypothesis are poorly focused and underdeveloped. Useful tips for surgical researchers are provided in Box 3 . Designing and developing an appropriate and relevant research question, hypothesis and objectives can be a difficult task. The critical appraisal of the research question used in a study is vital to the application of the findings to clinical practice. Focusing resources, time and dedication to these 3 very important tasks will help to guide a successful research project, influence interpretation of the results and affect future publication efforts.
FINER = feasible, interesting, novel, ethical, relevant; PICOT = population (patients), intervention (for intervention studies only), comparison group, outcome of interest, time.
Competing interests: No funding was received in preparation of this paper. Dr. Bhandari was funded, in part, by a Canada Research Chair, McMaster University.
Talk to Our counsellor: 9916082261
Practice Questions – Write short note on Importance and Sources of Hypothesis in Sociological Research. [ UPSC 2008]
Approach – Introduction, What makes Hypothesis relevant in a sociological research?, What are the sources which aids us to derive hypothesis?, Conclusion
INTRODUCTION
A hypothesis is a prediction of what will be found at the outcome of a research project and is typically focused on the relationship between two different variables studied in the research. It is usually based on both theoretical expectations about how things work and already existing scientific evidence.
We know that research begins with a problem or a felt need or difficulty. The purpose of research is to find a solution to the difficulty. It is desirable that the researcher should propose a set of suggested solutions or explanations of the difficulty which the research proposes to solve. Such tentative solutions formulated as a proposition are called hypotheses. The suggested solutions formulated as hypotheses may or may not be the real solutions to the problem. Whether they are or not is the task of research to test and establish.
DEFINTITIONS
TYPES OF HYPOTHESIS
i) Explanatory Hypothesis : The purpose of this hypothesis is to explain a certain fact. All hypotheses are in a way explanatory for a hypothesis is advanced only when we try to explain the observed fact. A large number of hypotheses are advanced to explain the individual facts in life. A theft, a murder, an accident are examples.
ii) Descriptive Hypothesis: Some times a researcher comes across a complex phenomenon. He/ she does not understand the relations among the observed facts. But how to account for these facts? The answer is a descriptive hypothesis. A hypothesis is descriptive when it is based upon the points of resemblance of some thing. It describes the cause and effect relationship of a phenomenon e.g., the current unemployment rate of a state exceeds 25% of the work force. Similarly, the consumers of local made products constitute asignificant market segment.
iii) Analogical Hypothesis : When we formulate a hypothesis on the basis of similarities (analogy), it is called an analogical hypothesis e.g., families with higher earnings invest more surplus income on long term investments.
iv) Working hypothesis : Some times certain facts cannot be explained adequately by existing hypotheses, and no new hypothesis comes up. Thus, the investigation is held up. In this situation, a researcher formulates a hypothesis which enables to continue investigation. Such a hypothesis, though inadequate and formulated for the purpose of further investigation only, is called a working hypothesis. It is simply accepted as a starting point in the process of investigation.
v) Null Hypothesis: It is an important concept that is used widely in the sampling theory. It forms the basis of many tests of significance. Under this type, the hypothesis is stated negatively. It is null because it may be nullified, if the evidence of a random sample is unfavourable to the hypothesis. It is a hypothesis being tested (H0). If the calculated value of the test is less than the permissible value, Null hypothesis is accepted, otherwise it is rejected. The rejection of a null hypothesis implies that the difference could not have arisen due to chance or sampling fluctuations.
USES OF HYPOTHESIS
i) It is a starting point for many a research work. ii) It helps in deciding the direction in which to proceed. iii) It helps in selecting and collecting pertinent facts. iv) It is an aid to explanation. v) It helps in drawing specific conclusions. vi) It helps in testing theories. vii) It works as a basis for future knowledge.
ROLE OF HYPOTHESIS
In any scientific investigation, the role of hypothesis is indispensable as it always guides and gives direction to scientific research. Research remains unfocused without a hypothesis. Without it, the scientist is not in position to decide as to what to observe and how to observe. He may at best beat around the bush. In the words of Northrop, “The function of hypothesis is to direct our search for order among facts, the suggestions formulated in any hypothesis may be solution to the problem, whether they are, is the task of the enquiry”.
First , it is an operating tool of theory. It can be deduced from other hypotheses and theories. If it is correctly drawn and scientifically formulated, it enables the researcher to proceed on correct line of study. Due to this progress, the investigator becomes capable of drawing proper conclusions. In the words of Goode and Hatt, “without hypothesis the research is unfocussed, a random empirical wandering. The results cannot be studied as facts with clear meaning. Hypothesis is a necessary link between theory and investigation which leads to discovery and addition to knowledge.
Secondly, the hypothesis acts as a pointer to enquiry. Scientific research has to proceed in certain definite lines and through hypothesis the researcher becomes capable of knowing specifically what he has to find out by determining the direction provided by the hypothesis. Hypotheses acts like a pole star or a compass to a sailor with the help of which he is able to head in the proper direction.
Thirdly , the hypothesis enables us to select relevant and pertinent facts and makes our task easier. Once, the direction and points are identified, the researcher is in a position to eliminate the irrelevant facts and concentrate only on the relevant facts. Highlighting the role of hypothesis in providing pertinent facts, P.V. Young has stated, “The use of hypothesis prevents a blind research and indiscriminate gathering of masses of data which may later prove irrelevant to the problem under study”. For example, if the researcher is interested in examining the relationship between broken home and juvenile delinquency, he can easily proceed in the proper direction and collect pertinent information succeeded only when he has succeed in formulating a useful hypothesis.
Fourthly , the hypothesis provides guidance by way of providing the direction, pointing to enquiry, enabling to select pertinent facts and helping to draw specific conclusions. It saves the researcher from the botheration of ‘trial and error’ which causes loss of money, energy and time.
Finally, the hypothesis plays a significant role in facilitating advancement of knowledge beyond one’s value and opinions. In real terms, the science is incomplete without hypotheses.
STAGES OF HYPOTHESIS TESTING
Formulating a hypothesis can take place at the very beginning of a research project, or after a bit of research has already been done. Sometimes a researcher knows right from the start which variables she is interested in studying, and she may already have a hunch about their relationships. Other times, a researcher may have an interest in a particular topic, trend, or phenomenon, but he may not know enough about it to identify variables or formulate a hypothesis. Whenever a hypothesis is formulated, the most important thing is to be precise about what one’s variables are, what the nature of the relationship between them might be, and how one can go about conducting a study of them.
Let us help you guide towards your career path We will give you a call between 9 AM to 9 PM
Join us to give your preparation a new direction and ultimately crack the Civil service examination with top rank.
© 2022 Achievers IAS Classes
Discover the world's research
IMAGES
VIDEO
COMMENTS
Simple hypothesis. A simple hypothesis is a statement made to reflect the relation between exactly two variables. One independent and one dependent. Consider the example, "Smoking is a prominent cause of lung cancer." The dependent variable, lung cancer, is dependent on the independent variable, smoking. 4.
2. Complex Hypothesis: A Complex hypothesis examines relationship between two or more independent variables and two or more dependent variables. 3. Working or Research Hypothesis: A research hypothesis is a specific, clear prediction about the possible outcome of a scientific research study based on specific factors of the population. 4.
A hypothesis is a tentative statement about the relationship between two or more variables. It is a specific, testable prediction about what you expect to happen in a study. It is a preliminary answer to your question that helps guide the research process. Consider a study designed to examine the relationship between sleep deprivation and test ...
A research hypothesis (also called a scientific hypothesis) is a statement about the expected outcome of a study (for example, a dissertation or thesis). To constitute a quality hypothesis, the statement needs to have three attributes - specificity, clarity and testability. Let's take a look at these more closely.
Developing a hypothesis (with example) Step 1. Ask a question. Writing a hypothesis begins with a research question that you want to answer. The question should be focused, specific, and researchable within the constraints of your project. Example: Research question.
Definition: Hypothesis is an educated guess or proposed explanation for a phenomenon, based on some initial observations or data. It is a tentative statement that can be tested and potentially proven or disproven through further investigation and experimentation. Hypothesis is often used in scientific research to guide the design of experiments ...
Essentially, a hypothesis is a tentative statement that predicts the relationship between two or more variables in a research study. It is usually derived from a theoretical framework or previous ...
A research hypothesis helps test theories. A hypothesis plays a pivotal role in the scientific method by providing a basis for testing existing theories. For example, a hypothesis might test the predictive power of a psychological theory on human behavior. It serves as a great platform for investigation activities.
A research hypothesis is a statement that proposes a possible explanation for an observable phenomenon or pattern. It guides the direction of a study and predicts the outcome of the investigation. A research hypothesis is testable, i.e., it can be supported or disproven through experimentation or observation. Characteristics of a good hypothesis
Formulating a hypothesis involves identifying research questions, conducting preliminary research, and crafting a clear and precise statement. A strong hypothesis is characterized by its testability, clarity, precision, and relevance to the research objectives. Common pitfalls in hypothesis writing include vague statements, overly complex ...
A research hypothesis, in its plural form "hypotheses," is a specific, testable prediction about the anticipated results of a study, established at its outset. It is a key component of the scientific method. Hypotheses connect theory to data and guide the research process towards expanding scientific understanding.
A research hypothesis provides a clear, testable statement that guides the direction and focus of a study. The benefit is that the hypothesis makes selecting appropriate research methods or statistical means possible, making the analysis more effective and achieving a result. Above all, the idea selected for the research also makes the study ...
A snapshot analysis of citation activity of hypothesis articles may reveal interest of the global scientific community towards their implications across various disciplines and countries. As a prime example, Strachan's hygiene hypothesis, published in 1989,10 is still attracting numerous citations on Scopus, the largest bibliographic database ...
A hypothesis is a prediction of what will be found at the outcome of a research project and is typically focused on the relationship between two different variables studied in the research. It is usually based on both theoretical expectations about how things work and already existing scientific evidence. Within social science, a hypothesis can ...
A hypothesis (from the Greek, foundation) is a logical construct, interposed between a problem and its solution, which represents a proposed answer to a research question. It gives direction to the investigator's thinking about the problem and, therefore, facilitates a solution. Unlike facts and assumptions (presumed true and, therefore, not ...
A research hypothesis is a specification of a testable prediction about what a researcher expects as the outcome of the study. It comprises certain aspects such as the population, variables, and the relationship between the variables. It states the specific role of the position of individual elements through empirical verification.
INTRODUCTION. Scientific research is usually initiated by posing evidenced-based research questions which are then explicitly restated as hypotheses.1,2 The hypotheses provide directions to guide the study, solutions, explanations, and expected results.3,4 Both research questions and hypotheses are essentially formulated based on conventional theories and real-world processes, which allow the ...
Here are a few different types of hypotheses: Simple hypothesis: A simple hypothesis predicts a relationship between an independent and a dependent variable. Complex hypothesis: A complex hypothesis looks at the relationship between two or more independent variables and two or more dependent variables. Empirical hypothesis: An empirical ...
Understanding the difference between a hypothesis and a theory is important in scientific research. A hypothesis is an educated guess or proposed explanation for a phenomenon, based on limited evidence and requiring further investigation. While, a theory is a well-substantiated explanation of an aspect of the natural world, supported by strong evid
Hypothesis is a prediction of the outcome of a study. Hypotheses are drawn from theories and research questions or from direct observations. In fact, a research problem can be formulated as a hypothesis. To test the hypothesis we need to formulate it in terms that can actually be analysed with statistical tools.
Research question. Interest in a particular topic usually begins the research process, but it is the familiarity with the subject that helps define an appropriate research question for a study. 1 Questions then arise out of a perceived knowledge deficit within a subject area or field of study. 2 Indeed, Haynes suggests that it is important to know "where the boundary between current ...
P. V. Yaung- The idea of a temporary but central importance that becomes the basis of useful research is called a working hypothesis. TYPES OF HYPOTHESIS. i) Explanatory Hypothesis: The purpose of this hypothesis is to explain a certain fact. All hypotheses are in a way explanatory for a hypothesis is advanced only when we try to explain the ...
rela onship between variables. When formula ng a hypothesis deduc ve. reasoning is u lized as it aims in tes ng a theory or rela onships. Finally, hypothesis helps in discussion of ndings and ...