assignment 4th week class 7

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Class 7 Assignment Answer 4th Week

Class 7 Assignment Answer 4th Week All Subject is available below. Class Seven Assignment Question and Solution, Assignment Solved Class 7, Four Week Class Seven Assignment Solution, 4th Week Class 7 Assignment Answer Sheet, Class 7 Assignment of 4th Week Will Publish For English, Science, Bangladesh and Global Students Subject. See Full Solution Class 7 Assignment Answer All Subject 4th Week.

Directorate of secondary and higher education has already released the assignment syllabus. You Must Submit Your Assignment Your School. See Class 7 Answer All Subject 4th Week Assignment. 

Class 7 Assignment Answer 4th Week:

Assignment Type: School / College Assignment 

4th Week Assignment Publish Date: 19 November 2020 

Assignment Class: 7 (Seven) 

Class 7 assignment answer 5th week, ৬ষ্ঠ থেকে ৯ম শ্রেণি পর্যন্ত এ্যাসাইনমেন্ট সম্পূর্ণ সমাধান (পঞ্চম সপ্তাহের জন্য).

NB: সকল শ্রেনীর প্রশ্ন সমাধানের কাজ চলছে। কিছুখন পর পর ভিজিট করে আপনার সমাধান নিয়ে নিন।

see/download School 4th Week Assignment Question Answer in below PDF: 

School 4th Week Assignment Question PDF

official Notice Link:  Click Here to see Official Notice

see/download School 4th Week Assignment Question Answer in below images: 

School Assignment Answer for Class 7:

সম্পূর্ণ সমাধান পাবেন নিচের লিঙ্কে.. click here.

৬ষ্ঠ থেকে ৯ম শ্রেণি পর্যন্ত এ্যাসাইনমেন্ট সমাধান (চতুর্থ সপ্তাহের জন্য) Click here

Class 7 English Assignment Answer

1. Rewrite the passage using correct form of verbs in the brackets.

Dear Masum,

Your letter regarding your joyful picnic came to me just now as a marvelous one. In your letter you have wanted to know about the picnic that we have enjoyed recently. Now I am writing to you about it. We, the students of class seven choose Sonargaon as our picnic spot. We were 30 in number. One of our teachers would be with us. We reached there at about 10 am. We have enjoyed the day very much. At last we returned home safely. We never will forget the day.

Homework: 2. Read your English grammar textbook from page no.83—89 and do the activities of Section B (i, ii and iii) 3. Choose the correct preposition from the list and fill in the gaps. (on, beside, at, about, in, of, into)

Homework Ans:

2. Read your English grammar textbook from page no.83—89 and do the activities of Section B (i, ii and iii)

i. Fill in the gaps with a/an or the and put a cross (X) where no article is needed:

A: Have you taken an appointment with Dr. Ehtesham?

B: Oh, yes. I have taken an appointment for tomorrow.

A Is the doctor not coming today?

B:No. The doctor comes to this hospital thrice a week.

A: When should we visit him tomorrow?

B: At 6:30p.m. I hope he will give us the best advice forproper diagnosis.

A: Tomorrow is the first day of the week. We have tostart for. The doctor earlier to avoid traffic congestion.

B: We shall reach the hospital before the sun sets.

ii. S: Good morning, teacher. How are you?

T: Good morning. Can you write a paragraph on Begum Rokeya?

S: Yes, I can.

T: What was she?

S: She was a social worker. She lived in undivided Bengal in the early 20th century.

T: She was a writer also. She wrote a number ofbooks.

S: Yes, teacher. I can mention the name of the book written

by her. “Sultana’s Dream” is the book written by her.

T: Where was she from?

S: She was from × Rangpur.

F: Anupom, what is the largest continent?

S: The Asia.

F: Give an example of the mangrove forest.

S:The Sunderbans.

F: Who is Stephen Hawkings?

S: He is a scientist. He is an English.

F: What was the objective of the language movement?

S: We demanded × Bangla to be declared as the state language.

3. Choose the correct preposition from the list and fill in the gaps. (on, beside, at, about, in, of, into)

At first take my cordial love. Hope you are safe and sound. Today I’m going to tell you about my reading room. The morning sun rays enters into it and there is enough space for air circulation. There are a reading table, a chair and a bookshelf in my room. If you come, you can see there are a world map, a wall clock and some beautiful wall mats hung upon the wall of my reading room. The bookshelf is kept beside the table. I like my reading room and I keep it neat and clean.

Class 7 Science Assignment Answer

প্রশ্ন ১: লিথিয়াম, পানি, খাবার লবন, চক, কার্বন, চুন, নাইট্রোজেন, পটাশিয়াম, অক্সিজেন, আয়ােডাইড, লােহা, ক্লোরিন ইত্যাদি কিছু পদার্থ।

ক) মৌলিক পদার্থ কাকে বলে?

খ) অণু ও পরমাণুর মধ্যে পার্থক্য লিখ।

গ) উদ্দীপকে উল্লেখিত পদার্থগুলােকে প্রতীক ও সংকেতের সাহায্যে প্রকাশ করে মৌলিক পদার্থ ও যৌগিক পদার্থ আলাদা কর।

ঘ) উল্লেখিত পদার্থগুলাের মধ্যে কাকে সার্বজনীন দ্রাবক বলা হয়? কারণ বিশ্লেষণ কর।

সংক্ষিপ্ত প্রশ্ন – ১ : চিনিকে কেন যৌগিক পদার্থ বলা হয়?

Class 7 Bangladesh & Global Studies BGS Assignment Answer

প্রশ্ন ১: একজন সুনাগরিক হিসেবে নিজেকে গড়ে তােলার ক্ষেত্রে তােমার যা করণীয় আছে তার একটি কর্মপরিকল্পনা তৈরি করাে।

প্রশ্ন ২: তােমার এলাকায় নির্বাচনের সময় যেসব নির্বাচনী আচরণবিধি পালন করা হয় তা বর্ণনা কর।

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Class 7 Assignment 4th Week 2021 Science & Charukola

June 4, 2021 bdexam-aid Assignment , dshe.gov.bd assignment 0

Class 7 Assignment 4th Week 2021 answer of Science and Charu Kola is available here in this post. ৪র্থ সপ্তাহ উত্তর ৭ম শ্রেণী is given in full detail here. In our website , you would get all class assignment solution for all class 8 9 7 and 6. We have given both class-wise and subject-wise assignment solution. In addition, we give you weekly assignment sample 2021 for you. As we have already posted subject-wise solution of all class 6 7 8 9. we are now going to give you class-wise all  2021 4th week assignment solution.

Quick Link..

Class 7 Assignment 4th Week 2021

Since Education Ministry postponed all institutional exam during this corona virus pandemic, the authority decided to take weekly assignment. Accordingly, the directorate of Secondary and Higher Education published assignment syllabus 2021. Until yet, they have publish 4th week assignment syllabus 2021. Our website has published all of the weekly assignment syllabus 2021. Moreover, we have given 1st, 2nd, 3rd and 4th week assignment solution in our website. However, at present we are going to give you 4th week assignment 2021 solution for class 7.        

Class 7 Assignment 4th Week (সকল বিষয়)

Class 7 Assignment for 4th Week English for all class has been published just now in the official website of Directorate of Secondary and Higher Education . You can download the 4th week English assignment syllabus from our website. But unfortunately you cannot enter into the official website right now. The official website is busy now. There are too many users entering at the same time in the official website. But you need not worry. We have already uploaded the 4th week English Assignment syllabus in our website. At first you need to see the 4th Week English Assignment syllabus along with other subjects. Click down to download 4th week English assignment syllabus.

Download 4th week assignment syllabus for class 7 PDF

As soon as the directorate of secondary Education published the assignment syllabus 2021, we have published the assignment syllabus in our website. Moreover, we have already given solution to all assignments of 4th week 2021. Now let us read Science assignment 4th week question first. Then we will upload class 7  science and charukola assignment answer. Look below to have Science and Charukola assignment 4th week 2021 question and answer.

Science Assignment Class 7 4th Week 

We are going to give you subject by subject assignment solution of 4th week here in the same post. You will get all 4th week assignment solution for class 7 in this post. Therefore you do not have to go to any other post. Already, we have given solution to all 4th week assignment answer for class 6 7 8 9. So, you can get any subject solution by visiting our website. However, let us now discuss 4th week science assignment topics or questions.

First of all, we will discuss questions of class 7 4th week assignment 2021. Then we will switch to class 7 science assignment 4th week 2021 answer. Afterwards you will get 4th week class 7 Charukola assignment solution as well. Go below to have class 7 assignment 4th week 2021 questions and answer.

Class 7 Science Assignment Questions

This is the 4th week English assignment topics. As you see the topics, those are not difficult for you to answer. You can solve this 2021 4th week assignment for class 7 without any effort. Yet we have provided 2021 4th week assignment solution for Class 7 Science for you. You just carefully read this science assignment answer. Then you will prepare your own assignment. Now you need to download class 7 assignment 4th week 2021 answer. For your convenience, we have given class seven Assignment answer in both JPG and PDF format. Click below to download the answer. 

Class 7 Science Assignment Solution

On the course of providing assignment solution to all high school classes, we will upload class 7 science assignment solution as well. Let us see what is there in the assignment syllabus first. Then we will give you the answer. The questions for science assignment fourth week are given below.   

Now download science assignment class 7 4th week from following. We have shared science assignment  in PDF. Click below to download science assignment fourth week class 7 answer.

Click here to download full answer PDF

4th Week Charukola Answer Class 7

Charukola assignment for class 7 includes some easy topics. We hope you can answer those questions yourself. Still if you face any difficulty in preparing you charukola 4th week assignment, you can see the following answer. Before giving you class 7 Charukola assignment answer, have a look at the assignment questions. The questions are in the following:

Now it is our turn to give you the 4th week Charukols answer for class 7. For your convenience, we have uploaded the class 7 charukola assignment answer both in JPG & PDF format. Click below to download 4th week Charukola assignment answer for class 7. 

That is all about class 7 assignment solution. So we have given you all 4th assignment solution in this post. No more. Good LUCK! 

See more below:

• Assignment Solution Class 7 1st Week 2021 বাংলা ইসলাম ও নৈতিক শিক্ষা
• Class 7 Assignment 2nd Week 2021 English BGS Answer
• Class 7 Assignment 3rd Week 2021 Math Krishi Shikkha/ Home Economics Answer
• 2nd Week English Assignment 2021 Class 8 7 6 9 Answer
• Class 9 Assignment 2021 Answer Science Bangla BGS 1st Week
• ৪র্থ সপ্তাহ উত্তর ৭ম শ্রেণী
• class 7 assignment 4th week 2021
• Class 7 Assignment 4th Week Solution
• science assignment class 7 4th week

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7 Class Bangladesh and Global Studies BGS Assignment 2022 – 4th Week

Secondary School Certificate authority publishes Class 7 BGS assignment answer 4th week 2022. They has been published 7 class BGS assignment full question solution, 2nd and 4th week. We also posted and you can get your 7 class Bangladesh and Global Studies assignment pictures 2022 and PDF files at chakrirkhobor.net. We try Bangladesh and Global Studies assignment full solution for class 7. Most of the Assignment finder many time fine BGS Assignment 7 Class pdf download. Like different classes, the position will uncover second week class 7 BGS Assignment Answer.

CLASS 7 BGS Assignment Answer 2022 – 4th Week

In this 2022 year all Education Board start all subject Assignment and will end on maybe December 2022. Class 7 Bangladesh and Global Studies assignments start in February and end in December 2022. Students can also check their Class 7 BGS 2nd paper assignments question solve on these websites. You can get the first class 7 BGS Assignment for Class 7 Exam 2022 all Board. This year newly start Assignment answer 2022 all board on their website.

How to do Class 7 Bangladesh and Global Studies Assignment Answer 2022?

We have talked about the full task class 7 BGS for every one of you. We trust you didn’t have any trouble in downloading any of the gave tasks. You can gather class 7 BGS Assignment arrangement from this post. Nonetheless, since the understudies need to offer their own input, they need to reply.

Are you Download 7 BGS assignment Answer 2022?

All time visit our site and Stay with us, You will get your answer. I will compose the 4th week class 7 BGS assignment task answers to the inquiries referenced in the inquiry concerning a help individual. In this post, we will be added the entire week task arrangement. You want to get CLASS 7 Assignment questions and answers to keep reading below.

BGS Assignment Solution Download 2022

CLASS 7 Education Board has recently released the notification regarding the class 7 Assignment Exam solution 2022 exam dates check on the official Website. All candidates who are filled the class 7 Assignment application form can download your Assignment 2022. CLASS Seven BGS 2022 PDF Download. I realize who lost his employment because of lockdown.

How to get Seven BGS paper Assignment Answer?

All education Board facilities get CLASS 7 BGS Answer. Well, it’s quite obvious most of the students in BGS are belongs from all area, they may not have the facility of Computer, Laptop or Android MOBILE, if you are not able to check your Assignment 4, then you can get your schools.

ইংরেজি এসাইনমেন্ট সমাধান Class 7- ২০২২- 4th week 

৭ম শ্রেণির গনিত এসাইনমেন্ট সমাধান- ২০২২-1st week , ৭ম শ্রেণির বাংলা এসাইনমেন্ট সমাধান- ২০২২-1st week , when seven class bgs assignment will be start 2022.

To whom it may concern & get bet Seven class BGS Assignment of All board and you try to see here. You cannot know to check and follow these rules.

4th Week Seven class BGS Assignment 2022

In conclusion, Every Assignment seeker knows chakrirkhobor.net published all type of Assignment with an answer pdf file. This Notice also found on my website. Finally, you can understand get the total subject class 7 Bangladesh and Global Studies Assignment all board 2022. So you have to connect for their address. In conclusion, for the next update about update assignment Notice. Finally 4th Week Seven Class BGS Assignment 2022 etc. So stay with us.

Class 7 4th Week Assignment 2022 Answer

We will now discuss how to create class 7 4th week assignment answer. As you all know, class 7 4th week assignment answer has been published today. Students who want to know the class 7 4th week assignment answer should do the full article. Today we will provide instructions for creating assignments. So that students can easily create class 7 4th week assignment answer.

We will also publish class 7 4th week assignment answer pdf format. Please read the following sections carefully to download the class 7 assignment answers from our website. So if you want to download class 7 4th week assignment answer then click on the section below.

Class 7 4th Week Assignment Answer

Today we will discuss class 7 4th week assignment answers. If you want to know the class 7 4th week Assignment Answer, then read the following sections. Because below the detailed information about the answer of the assignment will be provided. Two subjects have been selected as class 7 4th week Assignment. The two subjects are English and Bangladesh and world identity. In the next step we will discuss English and Bangladesh and world identity in detail. So that it is convenient to class 7 4th week Assignment Answer. Also click below to download our class 7 4th week Assignment Answer pdf.

Class 7 4th Week English Assignment Answer

As you all know this is the second determining work of class 7 4th week English assignment. The second determining work has been selected from Unit-3 and Unit-4. As part of the 4th week English assignment for the 4th week, make a list of the names of some of the people to whom you are grateful. We are benefited by different people at different times. That is why we are grateful to them. We need to make a list of a few events or people that we are grateful to have benefited from at different times for different reasons.

If we can answer the class 7 4th week English assignment correctly, we will be able to know about different people. Also learn about different jobs. Through today’s assignment, students will gain experience in writing short essays. The assignment guidelines must be carefully reviewed before creating class 7 4th week English assignment answer. The figure shows the English assignment guidelines for the 4th week of class 7. Click on the link below to download our class 7 4th week English assignment answer PDF.

Get Class 7 English 4th Week Assignment Answer

Class 7 4th Week Bangladesh and World Identity Assignment Answer

This is the second assignment on class 7 4th week Bangladesh and World Identity. The second assignment on Bangladesh and World Identity has been selected from the second chapter. The title of the second chapter is the culture and cultural diversity of Bangladesh. The work of class 7 4th week Bangladesh and World Identity Assignment should be done to determine the cultural differences between the rural and urban Bengali ethnic groups by mentioning the reasons for the diversity of cultural symbols from the traditional customs of Bangladesh.

In order to answer the class 7 4th week Bangladesh and World Identity Assignment, one has to know about the religion, language and community of different socio-cultural groups of Bangladesh. You need to know about the culture of villages and cities of Bangladesh. Also need to know about the folk culture of Bangladesh and its elements. Also need to know about the ethnic groups of Bangladesh and their cultural practices. Click on the link below to download our class 7 4th week Bangladesh and World Identity Assignment Answer PDF.

Get Class 7 Bangladesh & Global Studies 4th Week Assignment Answer

Class 7 4th Week Assignment Answer PDF Download

Today we discussed how to create class 7 4th week Assignment Answer. If you want to know better about the class 7 4th week Assignment Answer then read the above sections carefully. Click on the link below to download our class 7 4th week assignment answer pdf.

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Class 7 Assignment Science ( বিজ্ঞান ) Answer 2021Ι [4th week]

October 21, 2022 Assignment

Class 7 (4th week) assignment is running. According to the dshe.gov.bd website, the 4th-week subject is Science  ( বিজ্ঞান ). This article is for the students who are searching the answer to class seven 4th week science ( বিজ্ঞান ) assignment. We have made the best and accurate answer for your betterment. So, you can download your science ( বিজ্ঞান ) assignment solution from our website without free cost.

As we published the previous 3 weeks assignment. So, You will get the 4th-week assignment on our website based on the topics. Your selected subjects for the 4th week’s assignment is Science ( বিজ্ঞান ). Besides, this subject, you will get Bangla, English, Mathematics, and other subject’s assignment according to the notice of dshe.gov.bd website.

Table of Contents

Class 7 Science( বিজ্ঞান ) Assignment Topics

Understanding topics is very important for answering any question. So, we provided the ( বিজ্ঞান ) topics so that you can answer the question easily. Don’t worry we will provide the answer based on the topics below. So, read the question carefully before writing your assignment.

•  তোমার বাড়ির দেওয়ালে অথবা আশপাশের দেওয়ালে যে সাদা ও সবুজ রঙ কি কারনে হয় বলে তুমি মনে করো?
•  তোমার শরীরে হালকা জ্বর ও ডায়রিয়া  কি কারনে হয় বলে তুমি মনে করো?
•  স্বাস্থ্যসম্মত পায়খানা ও নিরাপদ পানি তোমার জীবনে কতটুকু গুরুত্ব বহন করে?- যৌক্তিকতা নিরূপণ করে ব্যাখ্যা করো।

According to the above question, you have to complete you science assignment. Click here to download the pdf of the question.

Class 7  Science ( বিজ্ঞান ) Assignment Answer

For free of cost, you can download the answer to class 7 ( বিজ্ঞান ) assignment from our allexamresult.com website. We always provide you the latest and most accurate answer. So, read the article carefully and download the best answer to the topics.

১ .  বাড়ির দেওয়ালে অথবা আশপাশের দেওয়ালে যে সাদা ও সবুজ রং দেখা যায় , তার কারণ কি বলে তুমি মনে কর?

বাড়ির দেওয়ালে অথবা আশপাশের দেওয়ালে যে সাদা ও সবুজ রং দেখা যায়, তার কারণ হলো শৈবাল। সমাঙ্গ বর্গের প্রধানত ক্লোরোফিলযুক্ত ও স্বভোজী উদ্ভিদরাই শৈবাল। এরা আলোকিত স্থান পছন্দ কর এরা মাটি, পানি, ঘরের দেওয়াল ও অন্য গাছের উপর জন্মাতে পারে। এদের দেহ এককোষী বা বহুকোষী হতে পারে। এদের দেহে কোন পরিবহন কলা থাকে না। এর সবুজ, লাল, বাদামী ইত্যাদি নানা রঙের হতে পারে। অতএব, বাড়ির দেওয়ালে অথবা আশপাশের দেওয়ালে যে সাদা ও সবুজ রঙ অণুজীবের কারণে হয়ে থাকে।

২. তোমার শরীরে হালকা জ্বর ও ডায়রিয়া  কি কারনে হয় বলে তুমি মনে করো?

আমার শরীরে হালকা জ্বর ও ডায়রিয়া অণুজীবের সংক্রমনের কারণে হয়।ব্যাকটেরিয়া জীবাণু দেহাভ্যন্তরে বিভিন্ন প্রক্রিয়ায় প্রবেশ করতে পারে । অপরিষ্কার হাত  জীবাণুর জন্য একটি সুবিধাজনক বাহন, যার মাধ্যমে সহজেই এরা মুখগহ্বরের ঢুকে যেতে পারে । আমরা যে জামা কাপড় ব্যবহার করি, তাতে লেগে ব্যাকটেরিয়ার স্পোর স্থানান্তরিত হতে পারে । বাতাসে ধুলাবালি উড়ে বেড়ায় তার সাথে অতি সহজেই ব্যাকটেরিয়া বা তার স্পোর এক স্থান থেকে অন্য স্থানে যেতে পারে। হাত মেলানোর মাধ্যমেও ব্যাকটেরিয়া একজন থেকে অন্যজনে অতি সহজে স্থানান্তরিত হতে পারে । পচা-বাসি খাবারের মাধ্যমে জীবাণু সহজেই ছড়ায় । ভাইরাস, ব্যাকটেরিয়া, ছত্রাক ও এন্টামিবা মানুষের শরীরের বিভিন্ন রোগ ছড়ায় ।

৩. স্বাস্থ্যসম্মত পায়খানা ও নিরাপদ পানি তোমার জীবনে কতটুকু গুরুত্ব বহন করে?- যৌক্তিকতা নিরূপণ করে ব্যাখ্যা করো।

যেখানে ‍সেখানে   মলমূত্র ত্যাগের কারণে স্বাস্থ্যজনিত সমস্যা সৃষ্টি হয়।   এসব মলমূত্রে যে জীবাণু থাকে তা ভক্ষণকারী অন্য জীব এগুলোকে ছড়িয়ে দেয় । এছাড়া বৃষ্টি বা জোয়ারের পানিতে এগুলো দূর দূরান্তে ছড়িয়ে পড়ে। আমাদের দেশের অনেক স্থানে স্বাস্থ্যসম্মত পায়খানা নেই এবং এসব অঞ্চলের মানুষ মাঠ বা কাঁচা পায়খানা ব্যবহার করে । এন্টামিবায় আক্রান্ত ব্যক্তির মল মাঠের মাটিতে মিশে যায়। এ মাটিতে হাত লাগলে বা এ মাটিতে যে সবজি চাষ করা হয় তাতে এসব জীবাণু লেগে থাকে । সবজির ভিতরেও এরা প্রবেশ করে। রান্নার পরেও দেখা যায়   ওই জীবাণু তখনও বেঁচে আছে ।

এভাবে এন্টামিবা সংক্রমিত হয় । ফলে সুস্থ মানুষও আক্রান্ত হয়ে পড়ে। খাবার – পানি নিরাপদ হওয়া খুবই জরুরী।   কলেরা ,  টাইফয়েড   ইত্যাদি ব্যাকটেরিয়া সৃষ্ট রোগ থেকে বাঁচতে অবশ্যই নিরাপদ পানি ব্যবহার করতে হবে। পান করা , গোসল ও কাপড় কাচা , বাসন ধোওয়া ইত্যাদির জন্য নিরাপদ পানি ব্যবহার করা উচিত ।   আর্সেনিকমুক্ত টিউবওয়েলের পানি নিরাপদ । পুকুর ও নদীর পানি ব্যবহারের পূর্বে ভালোভাবে ফুটিয়ে নিতে হবে । অন্যথায় , আর্সেনিকে আক্রান্ত হয়ে অনেক মানুষের মৃত্যু ঘটতে পারে  

Download Pdf of Class 7 science ( বিজ্ঞান ) assignment Answer

You can download the pdf of the Class 7 science ( বিজ্ঞান ) assignment Answer instead of writing from online. Here, we deliver you the pdf of the answer so that you can write the answer offline. You can also download the images of the answer. Click here to download the pdf of the Class 7 science ( বিজ্ঞান ) assignment Answer.

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অষ্টম শ্রেণীর 2022 শিক্ষাবর্ষের শিক্ষার্থীদের তৃতীয় সপ্তাহের অ্যাসাইনমেন্ট এর জন্য নির্ধারিত বিষয় এবং বিষয়ভিত্তিক প্রশ্ন …

4th Week Class 7 General Science (Biggan) Assignment Answer

4th Week Class 7 General Science (Biggan) Assignment Answer ! The Directorate of Secondary and Higher Education (www.dshe.gov.bd) board official website publish Class 7 General Science Assignment Syllabus for 4 th Week as soon as possible. After publishing the Class Seven Assignment Syllabus and Question, the Class 7 students are searching for 100% correct answer for Class 7 General Science Assignment 2020.

So, we hope this content is very much interested for our Class 7 students. Because today we are going to write all the important information about the Class 7 General Science Assignment Answer 2020. So, staying with us and regally visit our website.

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General Science Assignment for Class 7 Syllabus 4 th Week:

The authority of the Bangladesh education board not published yet, the “Week 4 General Science Assignment for Class 7 Syllabus”. When they published, we update here instantly.

4 th Week General Science Assignment Answer for Class 7:

This is very important for every Class Seven students to submit their fourth week Class 7 General Science Assignment Answer 2020. So, they are looking for the best solution of 4 th week Class 7 General Science Assignment.

What is the Official website for Class 7 Assignment Answer Download 2020?

The official website of the Directorate of Secondary and Higher Education (www.dshe.gov.bd) officially published all Classes Answers like Class 6 Assignment Syllabus & Answer , Class 7 Assignment Syllabus & Answer , Class 8 Assignment Syllabus & Answer , and Class 9 Assignment Syllabus & Answer . In this content, we only write about Class Seven General Science Assignment Answers/Solutions. But, you want to know about the Class 6, 7, 8, 9 Assignment Syllabus & Answers. Just click the above link. If you want to get subject wise Class Six Assignment Answer 2020, Just follow below.

How to Write Class 7 General Science Assignment Answer 2020?

Everybody has known that the Bangladeshdesh Education Board close all Schools, colleges & universities for Corona Virus. So, there is no way to Verification sorting, which students is good and which students are medium and bad. So, the Directorate of Secondary and Higher Education board wants to make their Class 6 to Class 9 Student next class roll by Assignment system. So, it is very important to write 100% correct Class 7 Assignment Answer and submit it properly.

Necessary Preparation

It is very important to the student of all classes including Class 7, have to make a mental preparation before starting to write down assignments answer. It is very important to make the assignment clean, clear, beautiful and attractive for good marks. Because it is said, ‘First philosophy then quality judgment’. So make an appropriate assignment you need to be focused on your work.

First, take some clean papers. Make a margin on them. Then start writing with a clear hand. Try to keep the words clean and easy to read. Don’t double write on it. And the most important thing for the assignment is the cover page. You have to take a page where your name, class, rolls, subject, assignment title will be written. And always give accurate answers in the assignment. Don’t make the answers very short or over lengthy, because it will make your teacher irritated and you won’t get a good mark.

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Class 7 Science Assignment 2021 Answer 4th Week

Class 7 Science Assignment 2021 Answer 4th Week Pic, PDF & HD Images! Today we are going to share the Second Week Class 7 Science Assignment Answer 2021. The Directorate of Secondary and Higher Education – DSHE.GOV.BD officially published the Class 6 to 9 Assignment Syllabus PDF .

Due to the COVID-19 reason, The Bangladesh Directorate of Secondary and Higher Education Board obedient to take assignments to continue the process of the student study. Every student of Class 6, 7, 8, 9 must be submitted the Assignment Answer to their class teacher. So, it is very important to collect the 100% correct Class 7 Assignment Answer Science 4th Week.

Every week, A Class 7 students need to write only 2 assignments. We know that this is not easy for a student to collect the Class 7 Assignment 4th Week Answer from online or off-line. But, TodayResultBD.com is always ready to provide quality answers of Class 7 Science  (Biggan) Assignment Answer 4th Week 2021.

Note that, TodayResultBD.com teams are working to provide 100% correct every week Assignment Answer of Class 6, Class 7, Class 8, and Class 9. So, regularly visit our website and collect your Assignment Solutions. Thanks.

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Class 7 Science (Biggan) Assignment 2021 Solution 4th Week:

Recently, the DSHE (Directorate of Secondary and Higher Education Board) published the 1st-week assignment for Class 7 students. Here below, you will find the Class 7 4th Week Assignment question and answer.

অ্যাসাইনমেন্ট বা নির্ধারিত কাজঃ

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What is the Official website for Class 6, 7, 8, 9 Assignment Answer Download 2021?

The official website of the Directorate of Secondary and Higher Education (www.dshe.gov.bd) officially published the all Classes Answers like as  Class 6 Assignment Answer ,  Class 7 Assignment Answer ,  Class 8 Assignment Answer  and  Class 9 Assignment Answer . In this content, we only write about Class Six Assignment Answers / Solutions. But, you want to know about the Class 6, 7, 8, 9 Assignment Syllabus & Answers. Just click the above link.

How to Write Class 7 Assignment Answer 2021?

Everybody has known that the Bangladesh Education Board close all Schools, colleges & universities for Corona Virus. So, there is no way to Verification sorting, which students are good and which students are medium and bad. So, the Directorate of Secondary and Higher Education board wants to make their Class 6 to Class 9 Student next class roll by Assignment system. So, it is very important to write 100% correct Class 7 Assignment Answer and submit properly.

Necessary Preparation:

It is very important to the student of all classes including Class 7, have to make a mental preparation before starting to write down assignments answer. It is very important to make the assignment clean, clear, beautiful, and attractive for good marks. Because it is said, ‘First philosophy then quality judgment’. So make an appropriate assignment you need to be focused on your work. First, take some clean papers. Make a margin on them. Then start writing with a clear hand. Try to keep the words clean and easy to read.

Don’t double write on it. And the most important thing for the assignment is the cover page. You have to take a page where your name, class, rolls, subject, assignment title will be written. And always give accurate answer in the assignment. Don’t make the answers very short or over lengthy, because it will make your teacher irritated and you won’t get a good mark.

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Class 7 Assignment 2022 (6th, 5th, 4th Week) Answer PDF

Class seven 1st & 2nd week assignment 2022 answer.

Class 7 Assignment Answer 2022 5th week and 4th week assignment ৭ম শ্রেণির assignment All Subjects Solution has been published on My website resultbd24.com. the Department of Secondary and Higher Education all assignment answers found here. Here you will find the correct answers to all the chapter based questions from the 3rd, 4th and 5th weeks.

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Class 7 Assignment 2022

You can find the full details about Class 7 6th Week Assignment Question PDF 2022 for All Subjects here. Here you will find answers to all week assignments in all subjects including Class 7 Math, Science, English and Bangladesh & Global Studies (BGS) from official website: www.dshe.gov.bd .

Students search on google for class seven all subject assignment solution we are provide all subject question answer here. Bangladesh all High School Class 7 Assignment Answer all Subject. Dhaka, Comilla, Jessore, Dinajpur, Jessore, Sylhet, Rajshahi, Madrasha Board Students Download her Assignment.

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Class 7 Assignment 2022 5th Week

Bangladesh all School Class 7 students get her all week assignment. DSHE 2nd Week Assignment then announced assignment so every Students of class 7 they solved her 5th week assignment Math & Science Subject.

গণিত সমাধানের জন্য এখানে ক্লিক করুন

বিজ্ঞান বিষয়ের উত্তর জন্য এখানে ক্লিক করুন

English Subject Class 7 Assignment to all Bangladeshi School Assignment 2022. Every student must do it at home and drop its high or online platform teacher judgment to all students and know students’ weaknesses. Students now download class 7 Assignment to all Students.

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Other Class Assignment

• Class 9 Assignment
• Class 8 Assignment
• Class six Assignment
• Class 7 5th Week Assignment PDF

When Class 7 5th Week Assignment published students download PDF here. Class seven class off for covid 19 so online assignment wise students education system running. After complete assignment students found assignment result and qualified for next class promotion.

Update: In 7th March 2022 will be published 5th week

2nd Week Assignment 2022 PDF Download For Class 7 and all Subject has been Published. Class Seven 1st week Assignment 2022 Answer Prepared here.

Class 7 Assignment 4th week

Class seven students they download her 2nd week assignment question download so students they found on here. Bangla, BGS subject question download.

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Class Seven Assignment 2022

Education Minister Dipu Moni on announced that students of classes 6-9 would be promoted to the next classes this year without any annual examinations. So school open not now they all students submitted her assignment Class 7 all Subject.

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Class 7 Assignment for Bangla, English, Math, Islam & Moral Studies, Hinduism, Buddhism, Christianity Religion, Information Communication Technology (ICT), Social Science subjects are available here.

Class 7 next week: 4th week

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Class 7 Bangladesh global Studies BGS Assignment Answer [Solution] 4th week 2022

First of all, today’s class 7 Bangladesh Global Studies BGS assignment answer 4th week 2022 will be published. Here we will solve 1st, 4th week assignments. Last week, we discussed the instructions for preparing the 1st week of your class 7 assignment. This week, you will learn how to prepare for the 4th week of your class 7 assignment solution. Anyway, If you want to get the class 7 4th week Bangladesh global Studies BGS assignment answer full information please follow the short information below.

Are you looking to answer the 4th week class 7 Bangladesh global Studies BGS assignment?  above all, you can download the answer right this place. We solved the 4th week with the class 7 Bangladesh global Studies BGS assignment & uploaded it here for your help. In addition, you can download it in a photo & PDF Format. In order to help them out, we have prepared an assignment solution for Bangladesh Global Studies BGS. Then let’s download the answers to your assignments below.

• class 7 Bangladesh global Studies BGS Assignment answer 2022 PDF

What is class 7 Bangladesh Global Studies BGS Assignment 4th week?

See class 7 3rd week bangladesh global studies bgs assignment answer pdf, how to get a bangladesh global studies bgs assignment answer in class 7, how to do the seventh class bangladesh global studies bgs assignment answer 4th week, how to do the class 7 bangladesh global studies bgs assignment launch.

The Education Board will start all subject Assignments in November and end in December 2022. class 7 assignments will also begin in November and end in December 2022. Students can also check their class 7 Bangladesh global Studies BGS assignments on these websites; After that, I will post the class 7 4th week assignment answers to the inquiries referenced in the inquiry concerning help to individuals I realise who lost their employment because of lockdown.

Assignment questions on the Bangladesh global Studies BGS subject of the 4th week of class tenth have been taken from the textbook. From the created part of the tenth-grade Bangladesh global Studies BGS textbook. Gain knowledge from all these lessons and solve 4th-week assignments.

class 7 Assignment Bangladesh global Studies BGS 4th week solution is very easy. You see the step-by-step follow the image file. We can share 4th week Bangladesh global Studies BGS assignment answers. You can check this answer for this assignment.

Similarly, All education Board facilities get class 7 Bangladesh global Studies BGS Assignment Answers. Most of the students in Bangladesh are from different areas, and they have access to a computer, laptop, or Android mobile. Now, bd-career.org can check your class 7 Bangladesh global Studies BGS subject assignment answer,  This website will help you.

In the event that you don’t consider the class 7 Bangladesh global Studies BGS Assignment, you may benefit substantially from another individual’s own input. Here, we will indicate how to finish the 4th week Bangladesh global Studies BGS Assignment of the seventh Class (class 7). This can be a conditionally sound decision, yet dependably ensure you are responding in time. Heading up!

DSHE has recently posted the notification regarding the class 7 Bangladesh Global Studies BGS Assignment in 2022 dates on its official website. Candidates who have already submitted their assignments can download their solutions. And next week’s assignment will be published on the official website at http://www.dshe.gov.bd/site/view/notices ; A direct link is provided below. 

Official Assignment Notice

We replied that the class 7 Bangladesh global Studies BGS Assignment has been published on our website. Further, we also discussed how to write correctly in the assignment and you can find the answer to all questions related to the class 7 Bangladesh global Studies BGS subject solved here.

Final Word:

In conclusion, Every student who submits an assignment knows that bd-career.org publishes all types of assignments with a file containing the answers. Basically, the class 7 assignment is answered in Bengali just like every other week and you will get answers when you visit our website. You can download the assignment if you wish and you do not have to pay any fees for it. You have any problems with comments with the Facebook comments box and stay with us.

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Class 7 Assignment 4th, 5th, 6th Week Answer Bangla, Kormo O Jibonmukhi Sikkha 2021

Class 7 Assignment Answer 4th, 5th, 6th week is available here for the Math, Bangla, Agriculture subject. From here reading this post one can easily download their class seven Assignment answer for this all week. We know class seven students want to collect their assignment syllabus along with its answer for the 4th week as well as it to be continued till the 6th week. Our expert team makes an assignment answer for class 7 students of this all week assignment. Check the below part of this post you will be able to collect all your answer to this class.

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Class 7 5th Week Assignment Syllabus

Class Seven 5th week assignment syllabus has been published recently. All the students of this class searching for this assignment syllabus. Because according to this they have to complete their class seven assignment answer. This assignment syllabus is responsible for the Directorate of Secondary and Higher Education (DSHE) authority. All this assignment syllabus information, notice you will find it there as well as our website. For downloading this 5th-week assignment syllabus of class 7 you need to click the below link. 

Assignment Syllabus Class 9, 8, 7, 6 NCTB 6th Week Short Syllabus www.dshe.gov.bd

Don’t think this is the end. We have some more information to provide you. After downloading this above assignment syllabus for your class. You need to make an assignment. Many of you may don’t be able to answer this assignment. So for their, we below provide the full answer to this assignment of class seven. Read this whole post and download your class assignment answer from the below link.

Class 7 Bangla Assignment 5th Week Answer 2021

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Class 7 Kormo O Jibonmukhi Assignment 5th Week Answer 2021

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Class 7 5th Week Assignment Answer

Class 7 5th week assignment answer you will find here. Searching for your class seven assignment answer but not finding the exact answer. Check this post we hope you will collect all your assignment answers from here. Class seven 6th week assignment NCTB Grammar and Composition part assignment. This assignment has two parts one is the writing part and another is for the grammar part. The Class 7 assignment 2nd paper task is a passage you have to rewrite using the correct form of the verb. From the assignment syllabus, you will find the full question of this 2nd paper English assignment which includes the Writing and Grammar Part. 

The DSHE authority gives class seven students an assignment they need to complete in time. In this assignment, there are some subjects for the 6th-week class seven students need to complete. English 2d paper subject is one of them you need to focus on very deeply. From the below download your class 7 English, Science, and BGS subject assignment answer.

Class 7 Math Assignment Answer (6th Week)

৭ম শ্রেনী কৃষি শিক্ষা এসাইনমেন্ট প্রশ্নের সমাধান ৬ষ্ঠ সপ্তাহ ২০২০ ডাউনলোড

Class 7 Bangla 6th Week Assignment Answer

Class 7 Assignment English Answer

Are you looking for your class 7 English Grammar assignment answer? Then here is this. From this website, you will find all of your English subject assignment answers for the 6th week. There have two-part to this English assignment. One of them is the Writing part and the other is the Grammar part. Now class seven students may feel very tense about how they can complete their Writing and grammar assignment part. No problem with this. Because we are here to provide you the exact answer to this two-part English assignment.

For downloading this English assignment answer includes this two-part you need to click the below link which we made for you. We hope from this you will find and collect your class English answer to this assignment.

Class 7 English Assignment 2nd Paper Grammar and Composition Answer -Rewrite the Passage

6th Week Assignment Answer Class 7 Science

Class 7 Science Assignment Answer Download. The DSHE authority released also class seven 5th week assignments on their website. You will also find this assignment syllabus with its answer from here. As the authority includes its science (biggan) subject assignment for this class students. This Science assignment task from their science textbook of the 6th chapter. Class seven students need to answer some questions from this 5th-week assignment which is given by the Education Authority.

The first two questions this class students need to answer from their direct biggan textbook. Also, you will find all your class assignment question answers from your science assignment Text-Book. For answering this assignment you need to read your textbook well. If you don’t want to make this assignment answer by your selves then just read your book and here we will give you the answer to his subject. Just check the below link and download your class seven assignment answer from here.

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Class Seven Science Answer Download

BGS Assignment Answer Class 7

Class 7 BGS Assignment Answer is also available here on our website. One can easily find this Bangladesh and Global Studies (BGS) subject answer from here. As many class seven students searching for this to make their this subject assignment answer. For answering this subject question students need to answer only two questions from this subject assignment to complete. For the 5th-week students need to read their BGS textbook chapters 5 and 6. And chapter 5 has only one lesson title called Qualities of a good citizen and in chapter 6 there is a chapter 3 lesson called election commission, electioneering area, and the last is called electioneering rules of conduct.

So all of this chapter question answers from the assignment have to done by the students. If anyone feels any hard doing this then he can download our assignment answer oft his BGS subject of class seven students. The question-answer is ready for you. Just click the below link and download this assignment answer.

BGS Answer Download

4th Week Assignment Answer & Syllabus for Class 6, 7, 8, 9

English Assignment Answer 2nd Paper Class 6, 7, 8, 9 Grammar and Composition 4th Week

ষষ্ঠ শ্রেণির এসাইনমেন্ট উত্তর ৩য়, ৪র্থ সপ্তাহ গণিত, ইংলিশ, কৃষি শিক্ষা, গ্রাহস্থ বিজ্ঞান, বিজ্ঞান, ইসলাম

Class 7 Assignment Answer 4th 5th 6th Week

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Class 7 Assignment 4th Week Answer 2022

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4th Week Class 7 Assignment Answer 2022 Pdf Answer

Are you Class 7 Students? Are you searching 4th Week Class 7 Assignment Answer 2022? The Board of Secondary And Higher Secondary Education of Bangladesh Publish Now class 7 4th Week Assignment Question and by official website. We have given now the 4th Week Class 7 Assignment Answer 2022. Already has effectively finished assignment 9 exams Now we work on 4th Week Assignment for the students in Class 7. It has been not so long since the exams wrapped up and students have already started searching for the Class 7 10th Week Assignment Answer .  are here to provide the updates you are looking for. So read this article completely without missing anything.

4th Week Class 7 Assignment Answer 2022 

The government of Bangladesh Runs many projects Online for Students. The assignment is the same project for Bangladeshi Class, with seven students. Already Bangladesh Government announces Class 7 10th Week assignment. 10 Week Class Seven 7 Assignment Will be held on BGS And Physical Helth Subject. Day by day we have given all Subject Answers on this page. If you are a student of Class 7 this post for you. Because we were given the answers of Bengali, English, religion, society, science, math assignment. So you read our post carefully. Now Given 10th Week Class 7 Assignment Answer.

Class 7 Math Assignment Answer

4th Week Class 7 English Assignment Answer 

Dear Students of Class 7. Who is searching online class seven 7 English assignment answer this post those students? Because we were given by this post-class 7 English 4th Week Assignment answer. Who is searching for the right answer for a full English assignment this post for them? To download class 7 English Assignment Online here. Now the Students of Class Seven. We know now searching for online English assignments to answer this post. Because we know English is the most important subject of another’s paper.  Because we were given by this post-class 7 English Assignment answer. Who is search the right answer for the full English assignment for this post for them? To download class 7 Englsh Assignment Online here.

Class 7 Assignment BGS  Answer 2022

The Bangladesh Government official website  DSHE Publish Class 7 Bangla Assignment For 10th Week 2022. You Can Collect Bangla Class 7 Assignment by Download. Class 7 assignment on Bangla is now available on the official website as well as on our website here. You know due to coved 19 Bangladesh government can,t taken any annual exam of class 7. For this class, seven students have taken this assignment. Which students will be attending and assignment and given this exam, these students will qualify next class. So this test is important for this class Seven Students.

Class 7 Assignment Answer 2022 Subject

For class Seven 7 is the 1 st time for the assignment held on all over Bangladesh. Students are worried for the assignment’s answer. As a result, we were given some ideas for the subject of the Class 7 Assignment. 1 st week to continue to Include subjects Bangla, English, Math, and also add Physics, Chemistry, Biology, Higher Math, Science, Essay, Information, and Communication Technology and Geography and environment. So we were given by this post Those Subject Answer.

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Education & result website in bangladesh, class 7 assignment answer 2021 4th week science & math.

August 8, 2022 allnewjob Assignment 26

Watch class 7 4th week assignment syllabus along with answer of Science, Bangla, Math, Agriculture and Arts and Crafts is available now. It is the period for sixth week assignment of the class seven students in Bangladesh. The understudies are, of course, very desperate for the answer of their class 7 4th assignment. As the submission of the assignment must be completed by this week, students need to be very active in studying. Our this blog post can have a little or great contribution to the class 7 assignment as the answer is here for download.

Class 7 Assignment

As the submission of the assignment must be completed by this week, students need to be very active in their studies. Over the past weeks we have noticed it distinctly that students have been demanding the syllabus when it was uploaded several days back. Though the students, not all of them, were unable to know that their 4th week assignment has appeared to the school. While a number of them have confirmed that they want to get online first.

There should be a clarification from our side why we are able to publish the assignment syllabus before your school knows. It is very simple because the directorate of secondary and higher education publish the assignment online. Your school needs to download it from online and print the copy and hand over to you. Therefore, the long process takes time in reaching the assignment to you. Therefore, you can choose us for supplying your class 7 4th week assignment syllabus and answer.

Assignment Class 7 Answer

Either you collect your class 7 4th week assignment from your school or online, it does not matter. Rather your submission matters to the teachers. And what is required for your assignment submission is the correct answer. Here, this is the valuable piece of paper we are giving you for free. The most skillful tutors of our group have been working since the beginning of November in 2020 to make answer for class 7 students’ assignment.

Students will have to submit assignment for at least three subjects : English, Science, and Bangladesh and Global Studies in the 4th week. Class 7 is also not exceptional in the sixth week assignment syllabus. Our class seven assignment of the 4th week has also appeared on our website. You do not need to visit a lot of websites for your class 7 assignment answer. Rather, if the learners wish to get, they will find class 7 all subject 4th week assignment answer in PDF and Image file.

4th Week Assignment Class 7 Science

4th assigned work for the class 7 students from the book is from chapter first of their general science book. This chapter discusses the structure of physics and relevant matters. The students will find out a description of three lines in question no 1 where the authority has given the name of some elements. Class 7 students have to answer the last two questions in the science assignment based on the above description in the 4th week.

The students have to write the answer of the first two questions from their science book as they are direct questions. You will find out the direct answer of the class 7 sixth week assignment answer in the text if you read it carefully. The last question in the class seven 4th week assignment is a short answer asking why sugar is a compound substance. Our students of class seven need not be so anxious for their 4th week assignment answer. Click on the below link and get your science assignment 4th assignment answer now.

Class 7 Arts and Crafts Assignment Answer

The assignment to arts and crafts has now entered in the 4th week for the class 7 learners. The answer to the relative subject is very easy to do but need a fine attachment. Every attachment on this website is very helpful for any class or level of education.  Thus, if you are sure to bring the success on you then, it might be very well in accordance to the assignment answer from you as a novice of class 7.

Generally, charu o karukola is a course of life and art in the syllabus of the class 7 learners. Through the arts and crafts children grow up to believe that they are very pioneers in the development of the humanitarian world. Therefore, studying this subject can bring a massive change in the mind of the learners along with the assignment answer under 4th week in 2021.

Class 7 Assignment Math Solution

4th week Math assignment for class 7 is from NCTB and composition textbook. In the assignment, the students have two parts-one is writing and another grammar. The class seven math 2nd paper assignment has the task of rewriting a passage using correct form of verbs. On the syllabus, you fill find the passage where some of the verbs are in the bracket. The students have to make the use of the right of verb corrected in your class 7 4th week assignment answer.

Class 7 students will also find a homework section for them to write in the assingment under 4th week. They have to read the page between 83-89 from the Class 7 Math book and must practice the activities of section B (i, ii, and iii).  The following answer you have to make as class seven math 4th week assignment is correcting preposition. In bracket, the directorate will give some preposition that needs to be filled at the appropriate place. 

Class 7 Math Assignment Full Solution 

Class 7 Home Science Assignment Solution

The Class 7 BGS assignments includes only two questions that need an elaborate answer on the qualities of a good citizen and Bangladesh election commission. From class 7 Bangladesh and Global Studies book, the students will find the answer of the 4th week from chapters five and six. Chapter five includes only one lesson titled the qualities of a good citizen while that of six adds lessons 3- election commission, electioneering area, and electioneering rules of conduct.

Class 7 students will have to create a work-plan that a good citizen does in accordance to the lesson 1 of your NCTB BGS book as 4th assignment answers. You have to point out the rules of conduct that are abided during the election that has happened in your locality recently.

Also Read the Following:

Class 7 English Assignment Answer & Solution (sixth & 3rd Week)  

Class 7 Math Assignment Answer / Solution School  

Assignment Class 7 Answer English, Banglসa, Math of all Week Solution

সপ্তম শ্রেণির গণিত এসাইনমেন্ট উত্তর / সমাধান ৫ম ও ৪র্থ সপ্তাহ

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26 Comments

5th week assintmnt Din class 7ar

fokir ans koi

tor …

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Answer questions koi

6th week are a ns koi

Thank Youuuuuuuuuuu

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Apnader onk speeling vul ase.please segula thik korben.

Where is the class 7 assignment ans theres nothin like the question

oii tora thambi

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4th Week Class 7 Science Assignment Answer 2021

The chapter-wish Answer for 4th Week class 7 Science has been collated in the form of PDFs that students can download for free and refer to the same while working on the NCTB questions. Class 7 Math Assignment Answer 2021 This year the NCTB has published the class 7 Science Assignment Answer with exemplar Problems designed and suggested by Subject experts of all Boards from the country, and they have published the latest or updated study material with exam material of Answer Answer with Exemplar Problems in class wise along with the student to all regional languages of the country.

Every Government and Private School Teaching Staff and Subject experts are suggested lesson wise solutions for all chapters of the assignment, we have suggested to every student and their parent can contact your child studying responsible school principle to get 4th week Class 7 Science Solutions & Exemplar Problems 2021  especially to your child studying medium based on the state education board.

Here we have provided direct links to download  Class 7 Assignment Science Subject wise Answer & Exemplar 2021 , every Education board student who is studying 1 st week of the Course from here can download each and every subject. Assignment Class

Class 7 Science Assignment Answer 2021

Class 7 Science  Assignment Answer 2021 covers all chapters prescribed in the latest  Class 7  Science Syllabus. Class six Science  Answer for class 7 by Testresultbd will be very helpful for all those students who are having trouble solving difficult problems. For better results, the students are advised to practice these Answer on a regular basis.

A brief overview of all chapters of the  Assignment Class 7 Science textbook  is provided below which will help students recall various concepts and topics studied in different chapters.

Class 7 School Assignment Science has announced a new syllabus for All Board Class 7 School Science Entrance Exam to Class 7th students to the academic year of 2021, the Bangladesh 7th Class entrance test is going to conduct in February and detailed notification with the complete schedule is already announced.

Every student who has applied to class 7th admission into high school society can follow the complete syllabus and new exam pattern for all medium students, those boy’s and girl’s students can follow Class 7 assignment Science Solution 2021  to getting a better idea about the exam syllabus.

Here we have shared those new answer details with High School 7th Class Assignment Answer 2021 Pdf published on the official website, follow the subject wise and chapter wise syllabus to get a better score for getting admission under NCTB.

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• Published: 13 May 2024

Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial

• Donna H. Ryan 1 ,
• Ildiko Lingvay   ORCID: orcid.org/0000-0001-7006-7401 2 ,
• John Deanfield 3 ,
• Steven E. Kahn 4 ,
• Eric Barros   ORCID: orcid.org/0000-0001-6613-4181 5 ,
• Bartolome Burguera 6 ,
• Helen M. Colhoun   ORCID: orcid.org/0000-0002-8345-3288 7 ,
• Cintia Cercato   ORCID: orcid.org/0000-0002-6181-4951 8 ,
• Dror Dicker 9 ,
• Deborah B. Horn 10 ,
• G. Kees Hovingh 5 ,
• Ole Kleist Jeppesen 5 ,
• Alexander Kokkinos 11 ,
• A. Michael Lincoff   ORCID: orcid.org/0000-0001-8175-2121 12 ,
• Sebastian M. Meyhöfer 13 ,
• Tugce Kalayci Oral 5 ,
• Jorge Plutzky   ORCID: orcid.org/0000-0002-7194-9876 14 ,
• André P. van Beek   ORCID: orcid.org/0000-0002-0335-8177 15 ,
• John P. H. Wilding   ORCID: orcid.org/0000-0003-2839-8404 16 &
• Robert F. Kushner 17  

Nature Medicine ( 2024 ) Cite this article

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In the SELECT cardiovascular outcomes trial, semaglutide showed a 20% reduction in major adverse cardiovascular events in 17,604 adults with preexisting cardiovascular disease, overweight or obesity, without diabetes. Here in this prespecified analysis, we examined effects of semaglutide on weight and anthropometric outcomes, safety and tolerability by baseline body mass index (BMI). In patients treated with semaglutide, weight loss continued over 65 weeks and was sustained for up to 4 years. At 208 weeks, semaglutide was associated with mean reduction in weight (−10.2%), waist circumference (−7.7 cm) and waist-to-height ratio (−6.9%) versus placebo (−1.5%, −1.3 cm and −1.0%, respectively; P  < 0.0001 for all comparisons versus placebo). Clinically meaningful weight loss occurred in both sexes and all races, body sizes and regions. Semaglutide was associated with fewer serious adverse events. For each BMI category (<30, 30 to <35, 35 to <40 and ≥40 kg m − 2 ) there were lower rates (events per 100 years of observation) of serious adverse events with semaglutide (43.23, 43.54, 51.07 and 47.06 for semaglutide and 50.48, 49.66, 52.73 and 60.85 for placebo). Semaglutide was associated with increased rates of trial product discontinuation. Discontinuations increased as BMI class decreased. In SELECT, at 208 weeks, semaglutide produced clinically significant weight loss and improvements in anthropometric measurements versus placebo. Weight loss was sustained over 4 years. ClinicalTrials.gov identifier: NCT03574597 .

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The worldwide obesity prevalence, defined by body mass index (BMI) ≥30 kg m − 2 , has nearly tripled since 1975 (ref. 1 ). BMI is a good surveillance measure for population changes over time, given its strong correlation with body fat amount on a population level, but it may not accurately indicate the amount or location of body fat at the individual level 2 . In fact, the World Health Organization defines clinical obesity as ‘abnormal or excessive fat accumulation that may impair health’ 1 . Excess abnormal body fat, especially visceral adiposity and ectopic fat, is a driver of cardiovascular (CV) disease (CVD) 3 , 4 , 5 , and contributes to the global chronic disease burden of diabetes, chronic kidney disease, cancer and other chronic conditions 6 , 7 .

Remediating the adverse health effects of excess abnormal body fat through weight loss is a priority in addressing the global chronic disease burden. Improvements in CV risk factors, glycemia and quality-of-life measures including personal well-being and physical functioning generally begin with modest weight loss of 5%, whereas greater weight loss is associated with more improvement in these measures 8 , 9 , 10 . Producing and sustaining durable and clinically significant weight loss with lifestyle intervention alone has been challenging 11 . However, weight-management medications that modify appetite can make attaining and sustaining clinically meaningful weight loss of ≥10% more likely 12 . Recently, weight-management medications, particularly those comprising glucagon-like peptide-1 receptor agonists, that help people achieve greater and more sustainable weight loss have been developed 13 . Once-weekly subcutaneous semaglutide 2.4 mg, a glucagon-like peptide-1 receptor agonist, is approved for chronic weight management 14 , 15 , 16 and at doses of up to 2.0 mg is approved for type 2 diabetes treatment 17 , 18 , 19 . In patients with type 2 diabetes and high CV risk, semaglutide at doses of 0.5 mg and 1.0 mg has been shown to significantly lower the risk of CV events 20 . The SELECT trial (Semaglutide Effects on Heart Disease and Stroke in Patients with Overweight or Obesity) studied patients with established CVD and overweight or obesity but without diabetes. In SELECT, semaglutide was associated with a 20% reduction in major adverse CV events (hazard ratio 0.80, 95% confidence interval (CI) 0.72 to 0.90; P  < 0.001) 21 . Data derived from the SELECT trial offer the opportunity to evaluate the weight loss efficacy, in a geographically and racially diverse population, of semaglutide compared with placebo over 208 weeks when both are given in addition to standard-of-care recommendations for secondary CVD prevention (but without a focus on targeting weight loss). Furthermore, the data allow examination of changes in anthropometric measures such as BMI, waist circumference (WC) and waist-to-height ratio (WHtR) as surrogates for body fat amount and location 22 , 23 . The diverse population can also be evaluated for changes in sex- and race-specific ‘cutoff points’ for BMI and WC, which have been identified as anthropometric measures that predict cardiometabolic risk 8 , 22 , 23 .

This prespecified analysis of the SELECT trial investigated weight loss and changes in anthropometric indices in patients with established CVD and overweight or obesity without diabetes, who met inclusion and exclusion criteria, within a range of baseline categories for glycemia, renal function and body anthropometric measures.

Study population

The SELECT study enrolled 17,604 patients (72.3% male) from 41 countries between October 2018 and March 2021, with a mean (s.d.) age of 61.6 (8.9) years and BMI of 33.3 (5.0) kg m − 2 (ref. 21 ). The baseline characteristics of the population have been reported 24 . Supplementary Table 1 outlines SELECT patients according to baseline BMI categories. Of note, in the lower BMI categories (<30 kg m − 2 (overweight) and 30 to <35 kg m − 2 (class I obesity)), the proportion of Asian individuals was higher (14.5% and 7.4%, respectively) compared with the proportion of Asian individuals in the higher BMI categories (BMI 35 to <40 kg m − 2 (class II obesity; 3.8%) and ≥40 kg m − 2 (class III obesity; 2.2%), respectively). As the BMI categories increased, the proportion of women was higher: in the class III BMI category, 45.5% were female, compared with 20.8%, 25.7% and 33.0% in the overweight, class I and class II categories, respectively. Lower BMI categories were associated with a higher proportion of patients with normoglycemia and glycated hemoglobin <5.7%. Although the proportions of patients with high cholesterol and history of smoking were similar across BMI categories, the proportion of patients with high-sensitivity C-reactive protein ≥2.0 mg dl −1 increased as the BMI category increased. A high-sensitivity C-reactive protein >2.0 mg dl −1 was present in 36.4% of patients in the overweight BMI category, with a progressive increase to 43.3%, 57.3% and 72.0% for patients in the class I, II and III obesity categories, respectively.

Weight and anthropometric outcomes

Percentage weight loss.

The average percentage weight-loss trajectories with semaglutide and placebo over 4 years of observation are shown in Fig. 1a (ref. 21 ). For those in the semaglutide group, the weight-loss trajectory continued to week 65 and then was sustained for the study period through week 208 (−10.2% for the semaglutide group, −1.5% for the placebo group; treatment difference −8.7%; 95% CI −9.42 to −7.88; P  < 0.0001). To estimate the treatment effect while on medication, we performed a first on-treatment analysis (observation period until the first time being off treatment for >35 days). At week 208, mean weight loss in the semaglutide group analyzed as first on-treatment was −11.7% compared with −1.5% for the placebo group (Fig. 1b ; treatment difference −10.2%; 95% CI −11.0 to −9.42; P  < 0.0001).

a , b , Observed data from the in-trial period ( a ) and first on-treatment ( b ). The symbols are the observed means, and error bars are ±s.e.m. Numbers shown below each panel represent the number of patients contributing to the means. Analysis of covariance with treatment and baseline values was used to estimate the treatment difference. Exact P values are 1.323762 × 10 −94 and 9.80035 × 10 −100 for a and b , respectively. P values are two-sided and are not adjusted for multiplicity. ETD, estimated treatment difference; sema, semaglutide.

Categorical weight loss and individual body weight change

Among in-trial (intention-to-treat principle) patients at week 104, weight loss of ≥5%, ≥10%, ≥15%, ≥20% and ≥25% was achieved by 67.8%, 44.2%, 22.9%, 11.0% and 4.9%, respectively, of those treated with semaglutide compared with 21.3%, 6.9%, 1.7%, 0.6% and 0.1% of those receiving placebo (Fig. 2a ). Individual weight changes at 104 weeks for the in-trial populations for semaglutide and placebo are depicted in Fig. 2b and Fig. 2c , respectively. These waterfall plots show the variation in weight-loss response that occurs with semaglutide and placebo and show that weight loss is more prominent with semaglutide than placebo.

a , Categorical weight loss from baseline at week 104 for semaglutide and placebo. Data from the in-trial period. Bars depict the proportion (%) of patients receiving semaglutide or placebo who achieved ≥5%, ≥10%, ≥15%, ≥20% and ≥25% weight loss. b , c , Percentage change in body weight for individual patients from baseline to week 104 for semaglutide ( b ) and placebo ( c ). Each patient’s percentage change in body weight is plotted as a single bar.

Change in WC

WC change from baseline to 104 weeks has been reported previously in the primary outcome paper 21 . The trajectory of WC change mirrored that of the change in body weight. At week 208, average reduction in WC was −7.7 cm with semaglutide versus −1.3 cm with placebo, with a treatment difference of −6.4 cm (95% CI −7.18 to −5.61; P  < 0.0001) 21 .

WC cutoff points

We analyzed achievement of sex- and race-specific cutoff points for WC by BMI <35 kg m − 2 or ≥35 kg m − 2 , because for BMI >35 kg m − 2 , WC is more difficult technically and, thus, less accurate as a risk predictor 4 , 25 , 26 . Within the SELECT population with BMI <35 kg m − 2 at baseline, 15.0% and 14.3% of the semaglutide and placebo groups, respectively, were below the sex- and race-specific WC cutoff points. At week 104, 41.2% fell below the sex- and race-specific cutoff points for the semaglutide group, compared with only 18.0% for the placebo group (Fig. 3 ).

WC cutoff points; Asian women <80 cm, non-Asian women <88 cm, Asian men <88 cm, non-Asian men <102 cm.

Waist-to-height ratio

At baseline, mean WHtR was 0.66 for the study population. The lowest tertile of the SELECT population at baseline had a mean WHtR <0.62, which is higher than the cutoff point of 0.5 used to indicate increased cardiometabolic risk 27 , suggesting that the trial population had high WCs. At week 208, in the group randomized to semaglutide, there was a relative reduction of 6.9% in WHtR compared with 1.0% in placebo (treatment difference −5.87% points; 95% CI −6.56 to −5.17; P  < 0.0001).

BMI category change

At week 104, 52.4% of patients treated with semaglutide achieved improvement in BMI category compared with 15.7% of those receiving placebo. Proportions of patients in the BMI categories at baseline and week 104 are shown in Fig. 4 , which depicts in-trial patients receiving semaglutide and placebo. The BMI category change reflects the superior weight loss with semaglutide, which resulted in fewer patients being in the higher BMI categories after 104 weeks. In the semaglutide group, 12.0% of patients achieved a BMI <25 kg m − 2 , which is considered the healthy BMI category, compared with 1.2% for placebo; per study inclusion criteria, no patients were in this category at baseline. The proportion of patients with obesity (BMI ≥30 kg m − 2 ) fell from 71.0% to 43.3% in the semaglutide group versus 71.9% to 67.9% in the placebo group.

In the semaglutide group, 12.0% of patients achieved normal weight status at week 104 (from 0% at baseline), compared with 1.2% (from 0% at baseline) for placebo. BMI classes: healthy (BMI <25 kg m − 2 ), overweight (25 to <30 kg m − 2 ), class I obesity (30 to <35 kg m − 2 ), class II obesity (35 to <40 kg m − 2 ) and class III obesity (BMI ≥40 kg m − 2 ).

Weight and anthropometric outcomes by subgroups

The forest plot illustrated in Fig. 5 displays mean body weight percentage change from baseline to week 104 for semaglutide relative to placebo in prespecified subgroups. Similar relationships are depicted for WC changes in prespecified subgroups shown in Extended Data Fig. 1 . The effect of semaglutide (versus placebo) on mean percentage body weight loss as well as reduction in WC was found to be heterogeneous across several population subgroups. Women had a greater difference in mean weight loss with semaglutide versus placebo (−11.1% (95% CI −11.56 to −10.66) versus −7.5% in men (95% CI −7.78 to −7.23); P  < 0.0001). There was a linear relationship between age category and degree of mean weight loss, with younger age being associated with progressively greater mean weight loss, but the actual mean difference by age group is small. Similarly, BMI category had small, although statistically significant, associations. Those with WHtR less than the median experienced slightly lower mean body weight change than those above the median, with estimated treatment differences −8.04% (95% CI −8.37 to −7.70) and −8.99% (95% CI −9.33 to −8.65), respectively ( P  < 0.0001). Patients from Asia and of Asian race experienced slightly lower mean weight loss (estimated treatment difference with semaglutide for Asian race −7.27% (95% CI −8.09 to −6.46; P  = 0.0147) and for Asia −7.30 (95% CI −7.97 to −6.62; P  = 0.0016)). There was no difference in weight loss with semaglutide associated with ethnicity (estimated treatment difference for Hispanic −8.53% (95% CI −9.28 to −7.76) or non-Hispanic −8.52% (95% CI −8.77 to 8.26); P  = 0.9769), glycemic status (estimated treatment difference for prediabetes −8.53% (95% CI −8.83 to −8.24) or normoglycemia −8.48% (95% CI −8.88 to −8.07; P  = 0.8188) or renal function (estimated treatment difference for estimated glomerular filtration rate (eGFR) <60 or ≥60 ml min −1  1.73 m − 2 being −8.50% (95% CI −9.23 to −7.76) and −8.52% (95% CI −8.77 to −8.26), respectively ( P  = 0.9519)).

Data from the in-trial period. N  = 17,604. P values represent test of no interaction effect. P values are two-sided and are not adjusted for multiplicity. The dots show estimated treatment differences, and the error bars show 95% CIs. Details of the statistical models are available in Methods . ETD, estimated treatment difference; HbA1c, glycated hemoglobin; MI, myocardial infarction; PAD, peripheral artery disease; sema, semaglutide.

Safety and tolerability according to baseline BMI category

We reported in the primary outcome of the SELECT trial that adverse events (AEs) leading to permanent discontinuation of the trial product occurred in 1,461 patients (16.6%) in the semaglutide group and 718 patients (8.2%) in the placebo group ( P  < 0.001) 21 . For this analysis, we evaluated the cumulative incidence of AEs leading to trial product discontinuation by treatment assignment and by BMI category (Fig. 6 ). For this analysis, with death modeled as a competing risk, we tracked the proportion of in-trial patients for whom drug was withdrawn or interrupted for the first time (Fig. 6 , left) or cumulative discontinuations (Fig. 6 , right). Both panels of Fig. 6 depict a graded increase in the proportion discontinuing semaglutide, but not placebo. For lower BMI classes, discontinuation rates are higher in the semaglutide group but not the placebo group.

Data are in-trial from the full analysis set. sema, semaglutide.

We reported in the primary SELECT analysis that serious adverse events (SAEs) were reported by 2,941 patients (33.4%) in the semaglutide arm and by 3,204 patients (36.4%) in the placebo arm ( P  < 0.001) 21 . For this study, we analyzed SAE rates by person-years of treatment exposure for BMI classes (<30 kg m − 2 , 30 to <35 kg m − 2 , 35 to <40 kg m − 2 , and ≥40 kg m − 2 ) and provide these data in Supplementary Table 2 . We also provide an analysis of the most common categories of SAEs. Semaglutide was associated with lower SAEs, primarily driven by CV event and infections. Within each obesity class (<30 kg m − 2 , 30 to <35 kg m − 2 , 35 to <40 kg m − 2 , and ≥40 kg m − 2 ), there were fewer SAEs in the group receiving semaglutide compared with placebo. Rates (events per 100 years of observation) of SAEs were 43.23, 43.54, 51.07 and 47.06 for semaglutide and 50.48, 49.66, 52.73 and 60.85 for placebo, with no evidence of heterogeneity. There was no detectable difference in hepatobiliary or gastrointestinal SAEs comparing semaglutide with placebo in any of the four BMI classes we evaluated.

The analyses of weight effects of the SELECT study presented here reveal that patients assigned to once-weekly subcutaneous semaglutide 2.4 mg lost significantly more weight than those receiving placebo. The weight-loss trajectory with semaglutide occurred over 65 weeks and was sustained up to 4 years. Likewise, there were similar improvements in the semaglutide group for anthropometrics (WC and WHtR). The weight loss was associated with a greater proportion of patients receiving semaglutide achieving improvement in BMI category, healthy BMI (<25 kg m − 2 ) and falling below the WC cutoff point above which increased cardiometabolic risk for the sex and race is greater 22 , 23 . Furthermore, both sexes, all races, all body sizes and those from all geographic regions were able to achieve clinically meaningful weight loss. There was no evidence of increased SAEs based on BMI categories, although lower BMI category was associated with increased rates of trial product discontinuation, probably reflecting exposure to a higher level of drug in lower BMI categories. These data, representing the longest clinical trial of the effects of semaglutide versus placebo on weight, establish the safety and durability of semaglutide effects on weight loss and maintenance in a geographically and racially diverse population of adult men and women with overweight and obesity but not diabetes. The implications of weight loss of this degree in such a diverse population suggests that it may be possible to impact the public health burden of the multiple morbidities associated with obesity. Although our trial focused on CV events, many chronic diseases would benefit from effective weight management 28 .

There were variations in the weight-loss response. Individual changes in body weight with semaglutide and placebo were striking; still, 67.8% achieved 5% or more weight loss and 44.2% achieved 10% weight loss with semaglutide at 2 years, compared with 21.3% and 6.9%, respectively, for those receiving placebo. Our first on-treatment analysis demonstrated that those on-drug lost more weight than those in-trial, confirming the effect of drug exposure. With semaglutide, lower BMI was associated with less percentage weight loss, and women lost more weight on average than men (−11.1% versus −7.5% treatment difference from placebo); however, in all cases, clinically meaningful mean weight loss was achieved. Although Asian patients lost less weight on average than patients of other races (−7.3% more than placebo), Asian patients were more likely to be in the lowest BMI category (<30 kg m − 2 ), which is known to be associated with less weight loss, as discussed below. Clinically meaningful weight loss was evident in the semaglutide group within a broad range of baseline categories for glycemia and body anthropometrics. Interestingly, at 2 years, a significant proportion of the semaglutide-treated group fell below the sex- and race-specific WC cutoff points, especially in those with BMI <35 kg m − 2 , and a notable proportion (12.0%) fell below the BMI cutoff point of 25 kg m − 2 , which is deemed a healthy BMI in those without unintentional weight loss. As more robust weight loss is possible with newer medications, achieving and maintaining these cutoff point targets may become important benchmarks for tracking responses.

The overall safety profile did not reveal any new signals from prior studies, and there were no BMI category-related associations with AE reporting. The analysis did reveal that tolerability may differ among specific BMI classes, since more discontinuations occurred with semaglutide among lower BMI classes. Potential contributors may include a possibility of higher drug exposure in lower BMI classes, although other explanations, including differences in motivation and cultural mores regarding body size, cannot be excluded.

Is the weight loss in SELECT less than expected based on prior studies with the drug? In STEP 1, a large phase 3 study of once-weekly subcutaneous semaglutide 2.4 mg in individuals without diabetes but with BMI >30 kg m − 2 or 27 kg m − 2 with at least one obesity-related comorbidity, the mean weight loss was −14.9% at week 68, compared with −2.4% with placebo 14 . Several reasons may explain the observation that the mean treatment difference was −12.5% in STEP 1 and −8.7% in SELECT. First, SELECT was designed as a CV outcomes trial and not a weight-loss trial, and weight loss was only a supportive secondary endpoint in the trial design. Patients in STEP 1 were desirous of weight loss as a reason for study participation and received structured lifestyle intervention (which included a −500 kcal per day diet with 150 min per week of physical activity). In the SELECT trial, patients did not enroll for the specific purpose of weight loss and received standard of care covering management of CV risk factors, including medical treatment and healthy lifestyle counseling, but without a specific focus on weight loss. Second, the respective study populations were quite different, with STEP 1 including a younger, healthier population with more women (73.1% of the semaglutide arm in STEP 1 versus 27.7% in SELECT) and higher mean BMI (37.8 kg m − 2 versus 33.3 kg m − 2 , respectively) 14 , 21 . Third, major differences existed between the respective trial protocols. Patients in the semaglutide treatment arm of STEP 1 were more likely to be exposed to the medication at the full dose of 2.4 mg than those in SELECT. In SELECT, investigators were allowed to slow, decrease or pause treatment. By 104 weeks, approximately 77% of SELECT patients on dose were receiving the target semaglutide 2.4 mg weekly dose, which is lower than the corresponding proportion of patients in STEP 1 (89.6% were receiving the target dose at week 68) 14 , 21 . Indeed, in our first on-treatment analysis at week 208, weight loss was greater (−11.7% for semaglutide) compared with the in-trial analysis (−10.2% for semaglutide). Taken together, all these issues make less weight loss an expected finding in SELECT, compared with STEP 1.

The SELECT study has some limitations. First, SELECT was not a primary prevention trial, and the data should not be extrapolated to all individuals with overweight and obesity to prevent major adverse CV events. Although the data set is rich in numbers and diversity, it does not have the numbers of individuals in racial subgroups that may have revealed potential differential effects. SELECT also did not include individuals who have excess abnormal body fat but a BMI <27 kg m − 2 . Not all individuals with increased CV risk have BMI ≥27 kg m − 2 . Thus, the study did not include Asian patients who qualify for treatment with obesity medications at lower BMI and WC cutoff points according to guidelines in their countries 29 . We observed that Asian patients were less likely to be in the higher BMI categories of SELECT and that the population of those with BMI <30 kg m − 2 had a higher percentage of Asian race. Asian individuals would probably benefit from weight loss and medication approaches undertaken at lower BMI levels in the secondary prevention of CVD. Future studies should evaluate CV risk reduction in Asian individuals with high CV risk and BMI <27 kg m − 2 . Another limitation is the lack of information on body composition, beyond the anthropometric measures we used. It would be meaningful to have quantitation of fat mass, lean mass and muscle mass, especially given the wide range of body size in the SELECT population.

An interesting observation from this SELECT weight loss data is that when BMI is ≤30 kg m − 2 , weight loss on a percentage basis is less than that observed across higher classes of BMI severity. Furthermore, as BMI exceeds 30 kg m − 2 , weight loss amounts are more similar for class I, II and III obesity. This was also observed in Look AHEAD, a lifestyle intervention study for weight loss 30 . The proportion (percentage) of weight loss seems to be less, on average, in the BMI <30 kg m − 2 category relative to higher BMI categories, despite their receiving of the same treatment and even potentially higher exposure to the drug for weight loss 30 . Weight loss cannot continue indefinitely. There is a plateau of weight that occurs after weight loss with all treatments for weight management. This plateau has been termed the ‘set point’ or ‘settling point’, a body weight that is in harmony with the genetic and environmental determinants of body weight and adiposity 31 . Perhaps persons with BMI <30 kg m − 2 are closer to their settling point and have less weight to lose to reach it. Furthermore, the cardiometabolic benefits of weight loss are driven by reduction in the abnormal ectopic and visceral depots of fat, not by reduction of subcutaneous fat stores in the hips and thighs. The phenotype of cardiometabolic disease but lower BMI (<30 kg m − 2 ) may be one where reduction of excess abnormal and dysfunctional body fat does not require as much body mass reduction to achieve health improvement. We suspect this may be the case and suggest further studies to explore this aspect of weight-loss physiology.

In conclusion, this analysis of the SELECT study supports the broad use of once-weekly subcutaneous semaglutide 2.4 mg as an aid to CV event reduction in individuals with overweight or obesity without diabetes but with preexisting CVD. Semaglutide 2.4 mg safely and effectively produced clinically significant weight loss in all subgroups based on age, sex, race, glycemia, renal function and anthropometric categories. Furthermore, the weight loss was sustained over 4 years during the trial.

Trial design and participants

The current work complies with all relevant ethical regulations and reports a prespecified analysis of the randomized, double-blind, placebo-controlled SELECT trial ( NCT03574597 ), details of which have been reported in papers describing study design and rationale 32 , baseline characteristics 24 and the primary outcome 21 . SELECT evaluated once-weekly subcutaneous semaglutide 2.4 mg versus placebo to reduce the risk of major adverse cardiac events (a composite endpoint comprising CV death, nonfatal myocardial infarction or nonfatal stroke) in individuals with established CVD and overweight or obesity, without diabetes. The protocol for SELECT was approved by national and institutional regulatory and ethical authorities in each participating country. All patients provided written informed consent before beginning any trial-specific activity. Eligible patients were aged ≥45 years, with a BMI of ≥27 kg m − 2 and established CVD defined as at least one of the following: prior myocardial infarction, prior ischemic or hemorrhagic stroke, or symptomatic peripheral artery disease. Additional inclusion and exclusion criteria can be found elsewhere 32 .

Human participants research

The trial protocol was designed by the trial sponsor, Novo Nordisk, and the academic Steering Committee. A global expert panel of physician leaders in participating countries advised on regional operational issues. National and institutional regulatory and ethical authorities approved the protocol, and all patients provided written informed consent.

Study intervention and patient management

Patients were randomly assigned in a double-blind manner and 1:1 ratio to receive once-weekly subcutaneous semaglutide 2.4 mg or placebo. The starting dose was 0.24 mg once weekly, with dose increases every 4 weeks (to doses of 0.5, 1.0, 1.7 and 2.4 mg per week) until the target dose of 2.4 mg was reached after 16 weeks. Patients who were unable to tolerate dose escalation due to AEs could be managed by extension of dose-escalation intervals, treatment pauses or maintenance at doses below the 2.4 mg per week target dose. Investigators were allowed to reduce the dose of study product if tolerability issues arose. Investigators were provided with guidelines for, and encouraged to follow, evidence-based recommendations for medical treatment and lifestyle counseling to optimize management of underlying CVD as part of the standard of care. The lifestyle counseling was not targeted at weight loss. Additional intervention descriptions are available 32 .

Sex, race, body weight, height and WC measurements

Sex and race were self-reported. Body weight was measured without shoes and only wearing light clothing; it was measured on a digital scale and recorded in kilograms or pounds (one decimal with a precision of 0.1 kg or lb), with preference for using the same scale throughout the trial. The scale was calibrated yearly as a minimum unless the manufacturer certified that calibration of the weight scales was valid for the lifetime of the scale. Height was measured without shoes in centimeters or inches (one decimal with a precision of 0.1 cm or inches). At screening, BMI was calculated by the electronic case report form. WC was defined as the abdominal circumference located midway between the lower rib margin and the iliac crest. Measures were obtained in a standing position with a nonstretchable measuring tape and to the nearest centimeter or inch. The patient was asked to breathe normally. The tape touched the skin but did not compress soft tissue, and twists in the tape were avoided.

The following endpoints relevant to this paper were assessed at randomization (week 0) to years 2, 3 and 4: change in body weight (%); proportion achieving weight loss ≥5%, ≥10%, ≥15% and ≥20%; change in WC (cm); and percentage change in WHtR (cm cm −1 ). Improvement in BMI category (defined as being in a lower BMI class) was assessed at week 104 compared with baseline according to BMI classes: healthy (BMI <25 kg m − 2 ), overweight (25 to <30 kg m − 2 ), class I obesity (30 to <35 kg m − 2 ), class II obesity (35 to <40 kg m − 2 ) and class III obesity (≥40 kg m − 2 ). The proportions of individuals with BMI <35 or ≥35 kg m − 2 who achieved sex- and race-specific cutoff points for WC (indicating increased metabolic risk) were evaluated at week 104. The WC cutoff points were as follows: Asian women <80 cm, non-Asian women <88 cm, Asian men <88 cm and non-Asian men <102 cm.

Overall, 97.1% of the semaglutide group and 96.8% of the placebo group completed the trial. During the study, 30.6% of those assigned to semaglutide did not complete drug treatment, compared with 27.0% for placebo.

Statistical analysis

The statistical analyses for the in-trial period were based on the intention-to-treat principle and included all randomized patients irrespective of adherence to semaglutide or placebo or changes to background medications. Continuous endpoints were analyzed using an analysis of covariance model with treatment as a fixed factor and baseline value of the endpoint as a covariate. Missing data at the landmark visit, for example, week 104, were imputed using a multiple imputation model and done separately for each treatment arm and included baseline value as a covariate and fit to patients having an observed data point (irrespective of adherence to randomized treatment) at week 104. The fit model is used to impute values for all patients with missing data at week 104 to create 500 complete data sets. Rubin’s rules were used to combine the results. Estimated means are provided with s.e.m., and estimated treatment differences are provided with 95% CI. Binary endpoints were analyzed using logistic regression with treatment and baseline value as a covariate, where missing data were imputed by first using multiple imputation as described above and then categorizing the imputed data according to the endpoint, for example, body weight percentage change at week 104 of <0%. Subgroup analyses for continuous and binary endpoints also included the subgroup and interaction between treatment and subgroup as fixed factors. Because some patients in both arms continued to be followed but were off treatment, we also analyzed weight loss by first on-treatment group (observation period until first time being off treatment for >35 days) to assess a more realistic picture of weight loss in those adhering to treatment. CIs were not adjusted for multiplicity and should therefore not be used to infer definitive treatment effects. All statistical analyses were performed with SAS software, version 9.4 TS1M5 (SAS Institute).

Reporting summary

Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article.

Data availability

Data will be shared with bona fide researchers who submit a research proposal approved by the independent review board. Individual patient data will be shared in data sets in a deidentified and anonymized format. Information about data access request proposals can be found at https://www.novonordisk-trials.com/ .

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Acknowledgements

Editorial support was provided by Richard Ogilvy-Stewart of Apollo, OPEN Health Communications, and funded by Novo Nordisk A/S, in accordance with Good Publication Practice guidelines ( www.ismpp.org/gpp-2022 ).

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First Department of Propaedeutic Internal Medicine, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

Alexander Kokkinos

Department of Cardiovascular Medicine, Cleveland Clinic, and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA

A. Michael Lincoff

Institute of Endocrinology & Diabetes, University of Lübeck, Lübeck, Germany

Sebastian M. Meyhöfer

Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

Jorge Plutzky

University of Groningen, University Medical Center Groningen, Department of Endocrinology, Groningen, the Netherlands

André P. van Beek

Department of Cardiovascular and Metabolic Medicine, University of Liverpool, Liverpool, UK

John P. H. Wilding

Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Robert F. Kushner

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Contributions

D.H.R., I.L. and S.E.K. contributed to the study design. D.B.H., I.L., D.D., A.K., S.M.M., A.P.v.B., C.C. and J.P.H.W. were study investigators. D.B.H., I.L., D.D., A.K., S.M.M., A.P.v.B., C.C. and J.P.H.W. enrolled patients. D.H.R. was responsible for data analysis and manuscript preparation. All authors contributed to data interpretation, review, revisions and final approval of the manuscript.

Corresponding author

Correspondence to Donna H. Ryan .

Ethics declarations

Competing interests.

D.H.R. declares having received consulting honoraria from Altimmune, Amgen, Biohaven, Boehringer Ingelheim, Calibrate, Carmot Therapeutics, CinRx, Eli Lilly, Epitomee, Gila Therapeutics, IFA Celtics, Novo Nordisk, Pfizer, Rhythm, Scientific Intake, Wondr Health and Zealand Pharma; she declares she received stock options from Calibrate, Epitomee, Scientific Intake and Xeno Bioscience. I.L. declares having received research funding (paid to institution) from Novo Nordisk, Sanofi, Mylan and Boehringer Ingelheim. I.L. received advisory/consulting fees and/or other support from Altimmune, AstraZeneca, Bayer, Biomea, Boehringer Ingelheim, Carmot Therapeutics, Cytoki Pharma, Eli Lilly, Intercept, Janssen/Johnson & Johnson, Mannkind, Mediflix, Merck, Metsera, Novo Nordisk, Pharmaventures, Pfizer, Regeneron, Sanofi, Shionogi, Structure Therapeutics, Target RWE, Terns Pharmaceuticals, The Comm Group, Valeritas, WebMD and Zealand Pharma. J.D. declares having received consulting honoraria from Amgen, Boehringer Ingelheim, Merck, Pfizer, Aegerion, Novartis, Sanofi, Takeda, Novo Nordisk and Bayer, and research grants from British Heart Foundation, MRC (UK), NIHR, PHE, MSD, Pfizer, Aegerion, Colgate and Roche. S.E.K. declares having received consulting honoraria from ANI Pharmaceuticals, Boehringer Ingelheim, Eli Lilly, Merck, Novo Nordisk and Oramed, and stock options from AltPep. B.B. declares having received honoraria related to participation on this trial and has no financial conflicts related to this publication. H.M.C. declares being a stockholder and serving on an advisory panel for Bayer; receiving research grants from Chief Scientist Office, Diabetes UK, European Commission, IQVIA, Juvenile Diabetes Research Foundation and Medical Research Council; serving on an advisory board and speaker’s bureau for Novo Nordisk; and holding stock in Roche Pharmaceuticals. C.C. declares having received consulting honoraria from Novo Nordisk, Eli Lilly, Merck, Brace Pharma and Eurofarma. D.D. declares having received consulting honoraria from Novo Nordisk, Eli Lilly, Boehringer Ingelheim and AstraZeneca, and received research grants through his affiliation from Novo Nordisk, Eli Lilly, Boehringer Ingelheim and Rhythm. D.B.H. declares having received research grants through her academic affiliation from Novo Nordisk and Eli Lilly, and advisory/consulting honoraria from Novo Nordisk, Eli Lilly and Gelesis. A.K. declares having received research grants through his affiliation from Novo Nordisk and Pharmaserve Lilly, and consulting honoraria from Pharmaserve Lilly, Sanofi-Aventis, Novo Nordisk, MSD, AstraZeneca, ELPEN Pharma, Boehringer Ingelheim, Galenica Pharma, Epsilon Health and WinMedica. A.M.L. declares having received honoraria from Novo Nordisk, Eli Lilly, Akebia Therapeutics, Ardelyx, Becton Dickinson, Endologix, FibroGen, GSK, Medtronic, Neovasc, Provention Bio, ReCor, BrainStorm Cell Therapeutics, Alnylam and Intarcia for consulting activities, and research funding to his institution from AbbVie, Esperion, AstraZeneca, CSL Behring, Novartis and Eli Lilly. S.M.M. declares having received consulting honoraria from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Daichii-Sankyo, esanum, Gilead, Ipsen, Eli Lilly, Novartis, Novo Nordisk, Sandoz and Sanofi; he declares he received research grants from AstraZeneca, Eli Lilly and Novo Nordisk. J.P. declares having received consulting honoraria from Altimmune, Amgen, Esperion, Merck, MJH Life Sciences, Novartis and Novo Nordisk; he has received a grant, paid to his institution, from Boehringer Ingelheim and holds the position of Director, Preventive Cardiology, at Brigham and Women’s Hospital. A.P.v.B. is contracted via the University of Groningen (no personal payment) to undertake consultancy for Novo Nordisk, Eli Lilly and Boehringer Ingelheim. J.P.H.W. is contracted via the University of Liverpool (no personal payment) to undertake consultancy for Altimmune, AstraZeneca, Boehringer Ingelheim, Cytoki, Eli Lilly, Napp, Novo Nordisk, Menarini, Pfizer, Rhythm Pharmaceuticals, Sanofi, Saniona, Tern Pharmaceuticals, Shionogi and Ysopia. J.P.H.W. also declares personal honoraria/lecture fees from AstraZeneca, Boehringer Ingelheim, Medscape, Napp, Menarini, Novo Nordisk and Rhythm. R.F.K. declares having received consulting honoraria from Novo Nordisk, Weight Watchers, Eli Lilly, Boehringer Ingelheim, Pfizer, Structure and Altimmune. E.B., G.K.H., O.K.J. and T.K.O. are employees of Novo Nordisk A/S.

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Nature Medicine thanks Christiana Kartsonaki, Peter Rossing, Naveed Sattar and Vikas Sridhar for their contribution to the peer review of this work. Primary Handling Editor: Sonia Muliyil, in collaboration with the Nature Medicine team.

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Extended data

Extended data fig. 1 effect of semaglutide treatment or placebo on waist circumference from baseline to week 104 by subgroups..

Data from the in-trial period. N  = 17,604. P values represent test of no interaction effect. P values are two-sided and not adjusted for multiplicity. The dots show estimated treatment differences and the error bars show 95% confidence intervals. Details of the statistical models are available in Methods . BMI, body mass index; CI, confidence interval; CV, cardiovascular; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; ETD, estimated treatment difference; HbA1c, glycated hemoglobin; MI, myocardial infarction; PAD, peripheral artery disease; sema, semaglutide.

Supplementary information

Reporting summary, supplementary tables 1 and 2.

Supplementary Table 1. Baseline characteristics by BMI class. Data are represented as number and percentage of patients. Renal function categories were based on the eGFR as per Chronic Kidney Disease Epidemiology Collaboration. Albuminuria categories were based on UACR. Smoking was defined as smoking at least one cigarette or equivalent daily. The category ‘Other’ for CV inclusion criteria includes patients where it is unknown if the patient fulfilled only one or several criteria and patients who were randomized in error and did not fulfill any criteria. Supplementary Table 2. SAEs according to baseline BMI category. P value: two-sided P value from Fisher’s exact test for test of no difference.

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Ryan, D.H., Lingvay, I., Deanfield, J. et al. Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial. Nat Med (2024). https://doi.org/10.1038/s41591-024-02996-7

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Received : 01 March 2024

Accepted : 12 April 2024

Published : 13 May 2024

DOI : https://doi.org/10.1038/s41591-024-02996-7

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