human physiology presentation topics

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161 Informative Physiology Topics To Check Out

Table of Contents

Structure of a physiological research paper, features of a good physiological essay, awesome physiological research topics, physiology research topics for college students, anatomy and physiology topics for research papers, human physiology research topics, interesting animal physiology topics, good animal reproduction physiology research topics for college essays, informative exercise physiology research topics, best clinical exercise physiology research topics.

As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, and cells carry out the chemical and physical functions in a living system. Some of its aspects include; medical physiology, animal, plant, cell, and comparative physiology.

With this, so many research works can be chosen from this field. Therefore as a student writing your essay on any physiology-related topic, you will have access to many medical journals, articles, encyclopedias, and thesis to aid your research paper, essay, or argument. We offer helpful online homework writing services to high school, college, and university students.

To assist students interested in physiological paper research, this section provides guidelines on how to effectively and efficiently arrange ideas, topics, subtopics, etc., to make for a coherent and accurate presentation. The following are notable structures and patterns to follow:

• Abstract: An abstract is an essential aspect in research papers and essays, and it is most often required that it is included in your essay or research. Primarily abstract appears at the beginning of a research essay. It details the essential points under your physiology paper topics.
• Introduction: This comes up at the beginning section of the essay or research paper. Just as its name implies, it introduces the paper, stating its purpose, goals, and objectives.
• Body: This is the most crucial part of a research paper. In this section, the student is expected to collect and arrange data that will persuade and intrigue the readers’ interest. It is also expected to be organized logically and partitioned into sections, using headings and subheadings to make for a chronological build-up.
• Conclusion: The essence of a conclusion is to restate the main topic. The conclusion reminds the reader of the basics of the research essay and reiterates the essential points in your essay.
• Reference List: This list contains all of the sources cited in the course of the research, and it usually appears at the end of the paper. It provides the necessary information on how to locate and retrieve cited sources in the text.

How can you ascertain a qualitative essay? How can you be convinced that your contributions to the physiological essays or research will be accepted? The following are great tips to consider to achieve this feat. They include:

• Clear Grammar: The application of language and the use of diction must be rich and concise. When the grammatical constructions applied are complex, then your work becomes too challenging to comprehend quickly, and this defeats the purpose of the essay. It is therefore advisable that you communicate in simple language.
• Conciseness: This involves the ability to communicate complete information about your research topic in as few words as possible. Your sentences should not contain unnecessary words, sentences, etc. but should be brief and to the point.
• Depth and Arguments: The arguments employed in your research writing must be intellectually profound. Looking at the different branches in physiology, you need to explore a particular branch whose arguments you can expand on. In doing this, you will be able to make your essay an engaging one. This, therefore, is a measure most readers often look out for.
• Clear Structure: Every research work must be structured chronologically. As a student, you are not expected to arrange your thoughts disjointedly; somewhat, you are expected to follow the proper model that your college professor or field has approved of the study

The study of physiology has already proven to be quite broad, spanning through various branches as it concerns the mechanisms in living systems. The following are physiological research topics that enable the students to focus on chosen aspects or branches of study. They include:

• Do some physical exercises lead to fatigue in women?
• Effects of cigar smoking on lung function
• Blood pressure changes during the menstrual cycle of older women.
• Dietary habits and their effects on the human body.
• Stress: Disease patterns and psychological stress in hypertensive men.
• The effects of pollution on the nutritional status of infants.
• Lactose intolerance in young adults: A case study.
• Adapting to cold temperatures: A Study on changes in the human body.
• Why are physical exercises crucially crucial for the psychological development of young children?
• Health Effects of Drugs on the Human Body.
• Dehydration and its predominant health effects.
• Weather as a tool for disrupting physiological processes.
• Vitamins as a one-way cure to health challenges.
• Cardiovascular Illnesses: Where it all begins.
• Bacteria metabolism in animals.
• Significant effects of environmental physiology.
• Stress and its effect on the human body.
• Exercises as a tool for redeeming the human body.
• The impact of climate change on marine animals.
• Eating disorders and their effect on the human body.

The following are samples of research topics that center on college students. These physiological psychology research topics include but are not limited to:

• The study of the effect of anti-diabetic drugs in men.
• Genetics and Developmental Stages: A case study of young females
• Age and Memory in older men.
• Stages of intellectual growth in humans.
• The assessment of the nutritional status of children between ages 7-12.
• Lactose intolerance in American Men
• Hemoglobin genotype in particular states
• Adapting to Physical Illnesses.
• Effects of salt deprivation and calcium load on blood pressure.
• The PH effect on Human erythrocyte Shape.
• Lactose intolerance in middle-aged women.
• Effect of cigarette smoking on lung function.
• Effect of excess salt intake on males and females
• The resulting influence of hemoglobin genotype in standard blood types.
• Research on the temperature and exercise on limb blood flow in man.
• Blood pressure, pulse, and respiratory rates in older people.
• Causes of Lactose intolerance in people
• Serum and urinary levels of sodium and potassium in normal adults.
• Blood flow with patients with diabetes.
• Blood pressure rates in older Nigerian Men.

This section focuses on the integral part of living organisms and creatures and possible research topics that can be found in that field. Here are some interesting anatomy and physiology topics:

• A study of the human body
• The Chemistry of Life in Humans and Animals.
• Structure of the Cell: A case study of the Human Cellular system.
• Anatomy and Physiology of the Tissues.
• The Human Skeletal System
• Functions of the Articular System
• Importance of the Muscular System
• Nervous System: Its Function to the Human Body
• The Endocrine System: What to Know about it.
• Blood Vessels in the Human Body
• Cardiovascular System in animals
• Lymphatic System in mammals
• Nutrition and the Digestive System: How they Function
• Respiratory System: A case study of the integral structure.
• Urinary System: Understanding your body.
• Reproductive System: What Organs are Responsible for Reproduction in man and mammals.
• Functions of the brain cell in animals.
• Structure of the skeletal system in reptiles.
• A study of the life cycle in Amphibians
• The importance of the heart in transfusing blood.

Human physiology studies how the human body works. That includes the chemistry and physics that support body functions. Here are some human physiology topics to write on:

• Effects of excessive blood pressure on human beings.
• A study of the effects of Salt deprivation on the human body
• A critical study on how the body can adapt to cold temperatures
• How weather influences the physiological processes of the human body
• The effect of dehydration on the human body
• The resulting consequences of stress on the human muscle
• The health defects of drug consumption and drug abuse
• A study of the peculiarities of the human body
• The resulting cause of cardiovascular illness in old people
• Can young people develop early-stage cardiovascular illness?
• The result of calcium overload in the body
• Effects of the excessive consumption of Vitamin C on the human body
• A study of the resulting cause of yeast infection in women
• A comparative analysis of the effect of excessive Vitamin C and Vitamin E in the human body
• Effects of the excessive consumption of caffeinated drinks on the body
• Drug abuse and its resulting consequences to the body
• The harmful effect of excessive consumption of Ibuprofen
• A study of the central gap in the stress theory
• An overview of the Oxytocin hypothesis
• A comparative study of pancreatic alpha-amylase and salivary alpha-amylase

Aside from studying the human body, physiology also extends to the study of the animal body. Here are some interesting physiology topics in this aspect:

• A study of the resulting cause of the death of wild animals in bonds
• What are the reasons for the increased death rate in wild animals in bonds?
• The use and importance of anesthetics for animals
• A study of the types of parasites and illnesses that affect animals
• A study of the various types of parasites and illnesses they cause
• The study of the respiratory system of an elephant
• Respiratory study of the animal’s body
• A research study of the body metabolism of a lion
• What are the metabolic characteristics of domestic animals?
• A study of the metabolic characters of a lion
• The resulting challenges of global warming in animals
• How climate change affects animal’s productivity
• A study of the peculiarities in particular wild animals
• Types of parasites that affect other animals
• The harmful effect of parasitic relationships between animals
• How symbiotic relationships benefits animals
• The benefits and effects of commensalism on animals
• A study of the death rate of domestic animals
• How animal cruelty shortens animal’s lifespan
• A study of the lifespan of animals in the cat family

Animal physiology also extends to look into animal reproduction. Here are some animal physiology research topics on reproduction to look into:

• Importance of animal reproduction
• How global warming affects animal reproduction
• Importance of nurturance for pregnant animals
• How to improve the pregnancy rate in farm animals
• Importance of farm animals reproduction to humans
• Challenges animals face during reproduction
• A study of the animal reproductive system
• Reproduction is an essential component in farm animals
• An overview of animal science reproduction practice
• Importance of animal welfare during reproduction

Physiology also extends to sports and exercise. If you need ideas for sports physiology research topics or physiological paper topics to assist you while preparing your class or individual proposal for your physiology research topics, below are some detailed physiological topics in the exercise aspect:

• The importance of regular exercise to the human body
• The treatment pattern for knee joint injuries in athletes
• A proper meal plan for athletes
• How athletes can increase their body metabolism
• The study of aggressiveness and physical exercise
• Best ways to introduce physical effects therapy for athletes
• Importance of physiotherapy to athletes
• Adverse effects of going through physical rehabilitation without the assistance of a physiotherapist
• Outdoor physical exercises to reduce anxiety
• A study of how physical exercise can manage depression
• The dangers of muscle sprains in athletes
• Best cure procedures for muscle sprains for everyone
• In depth analysis of the effect of excessive consumption of caffeine on athletes
• Ways to prevent muscle fiber destruction during exercise
• Importance of engaging in physical exercise to the mental health
• A study on how physical exercise alleviates autism symptoms
• Why physical exercise is essential to the body
• Exercise therapy as a treatment for specific athletic injuries
• Importance of health nutrition plans for athletes
• Dangers of sprains to athletes

While still basing your physiology topics for research papers on the exercise aspect, you can look into clinical exercise topics. Here are some of them:

• Importance of cognitive assessment in athletes during physical exercise
• Exercise physiology for disabled people
• The use of placement support and supervision during clinical exercise physiology
• Physical exercise and clinical physiology
• The importance of clinical physiology exercise
• The limits of clinical exercise physiology
• Exercise effects on older people
• A critical analysis of inflight exercise
• The evaluation of clinical exercise physiology on humans
• A clinical examination and reading of specific physical exercises
• Talk Test therapy in patients
• A study of the Talk Test response practice in cardiac patients
• Temporal stability of pacing strategy in patients
• A study of the challenges of speech passage during a Talk Test response
• Physiological responses during a log rolling
• Relative exercise levels and battle rope training in males
• How does foam rolling affect flexibility in young adults.
• Physiological responses to water cycling.
• Work out planning using results versus predictions of maximal HR
• Accessing body composure: Accuracy of the lean screen app.
• Research on how wearing a cold vest affects energy expenditure
• Talk Test in children: Essential Tool in Child Physiotherapy
• Regulating work out levels using the Talk Test in Children
• Physiological responses during yoga exercises.
• Physiological responses on the treadmill.
• A study of the effects of Tabata training
• The use duration as a Talk Test response strategy
• Racing: Effect of pace variations.
• Walking as a tool to redeem the body’s fitness
• Training results of altitude masks

Schoolwork can become hectic to manage at times, and you might require professional biology homework help or research assistance. Be assured that there are reliable experts in this field, and are the best choice when you decide to do homework for money . They are ENL writers, professors, teachers that will provide you with custom written works that will gain you the best grades, all at a quick turnaround time and cheap rate.

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Unit 1: Introduction to human body systems

About this unit.

Get introduced to the major organ systems of the human body! You’ll learn some general anatomy (a roadmap of your body), learn how the arm bone actually connects to the shoulder bone, and how the different organs work together to keep you alive. Watch some videos, read some articles, try some flashcards, and then quiz yourself!

Circulatory system introduction

• Meet the heart! (Opens a modal)
• Flow through the heart (Opens a modal)
• Two circulations in the body (Opens a modal)
• The heart is a double pump (Opens a modal)
• Lub dub (Opens a modal)
• Parts of the heart (Opens a modal)
• Arteries vs. veins - what's the difference? (Opens a modal)
• Arteries, arterioles, venules, and veins (Opens a modal)
• What is blood pressure? (Opens a modal)

Respiratory system introduction

• Meet the lungs! (Opens a modal)
• People and plants (Opens a modal)
• The bronchial tree (Opens a modal)
• Inhaling and exhaling (Opens a modal)
• How does lung volume change? (Opens a modal)
• Thermoregulation in the lungs (Opens a modal)
• The lungs and pulmonary system (Opens a modal)

Hematologic system introduction

• What's inside of blood? (Opens a modal)
• Red blood cells (Opens a modal)
• Blood types (Opens a modal)
• Hemoglobin (Opens a modal)
• Hemoglobin moves O2 and CO2 (Opens a modal)
• Hemostasis (Opens a modal)

Endocrine system introduction

• Endocrine gland hormone review (Opens a modal)
• The hypothalamus and pituitary gland (Opens a modal)
• Hormone concentration metabolism and negative feedback (Opens a modal)
• Types of hormones (Opens a modal)
• Cellular mechanism of hormone action (Opens a modal)

Nervous system introduction

• Anatomy of a neuron (Opens a modal)
• Structure of the nervous system (Opens a modal)
• Functions of the nervous system (Opens a modal)
• Introduction to neural cell types (Opens a modal)
• Overview of neuron function (Opens a modal)
• Synapse structure (Opens a modal)
• Neuronal synapses (chemical) (Opens a modal)
• Types of neurotransmitters (Opens a modal)
• Types of neurotransmitter receptors (Opens a modal)

Gastrointestinal system introduction

• Meet the gastrointestinal tract! (Opens a modal)
• Mouth (Opens a modal)
• Esophagus (Opens a modal)
• Stomach (Opens a modal)
• Small intestine 1: Structure (Opens a modal)
• Small intestine 2: Digestion (Opens a modal)
• Small intestine 3: Absorption (Opens a modal)
• Liver (Opens a modal)
• Biliary tree (Opens a modal)
• Exocrine pancreas (Opens a modal)
• Endocrine pancreas (Opens a modal)
• Colon, rectum, and anus (Opens a modal)

Musculoskeletal system introduction

• Myosin and actin (Opens a modal)
• How tropomyosin and troponin regulate muscle contraction (Opens a modal)
• Anatomy of a skeletal muscle cell (Opens a modal)
• Neuromuscular junction, motor end-plate (Opens a modal)
• Three types of muscle (Opens a modal)
• Type 1 and type 2 muscle fibers (Opens a modal)
• Skeletal structure and function (Opens a modal)
• Microscopic structure of bone - the Haversian system (Opens a modal)

Reproductive system introduction

• Welcome to the reproductive system (Opens a modal)
• Anatomy of the male reproductive system (Opens a modal)
• Transport of sperm via erection and ejaculation (Opens a modal)
• Spermatogenesis (Opens a modal)
• Testosterone (Opens a modal)
• Basics of egg development (Opens a modal)
• The ovarian cycle (Opens a modal)
• Meet the placenta! (Opens a modal)
• Reproductive cycle graph - Follicular phase (Opens a modal)
• Reproductive cycle graph - Luteal phase (Opens a modal)
• Estrogen (Opens a modal)
• Breast anatomy and lactation (Opens a modal)

Immunologic system introduction

• Role of phagocytes in innate or nonspecific immunity (Opens a modal)
• Types of immune responses: Innate and adaptive, humoral vs. cell-mediated (Opens a modal)
• B lymphocytes (B cells) (Opens a modal)
• Professional antigen presenting cells (APC) and MHC II complexes (Opens a modal)
• Helper T cells (Opens a modal)
• Cytotoxic T cells (Opens a modal)
• Review of B cells, CD4+ T cells and CD8+ T cells (Opens a modal)
• Clonal selection (Opens a modal)
• Self vs. non-self immunity (Opens a modal)
• How white blood cells move around (Opens a modal)
• Inflammatory response (Opens a modal)
• Blood cell lineages (Opens a modal)

Urinary system introduction

• Meet the kidneys! (Opens a modal)
• Kidney function and anatomy (Opens a modal)
• Glomerular filtration in the nephron (Opens a modal)
• Changing glomerular filtration rate (Opens a modal)
• Countercurrent multiplication in the kidney (Opens a modal)
• Urination (Opens a modal)
• The kidney and nephron (Opens a modal)
• Secondary active transport in the nephron (Opens a modal)
• Introductory urinary system quiz 10 questions Practice
• Intermediate urinary system quiz 7 questions Practice
• Advanced urinary system quiz 4 questions Practice

Integumentary system introduction

• Meet the skin! (Overview) (Opens a modal)
• What is skin? (Epidermis) (Opens a modal)
• What lies beneath the epidermis? (Dermis and Hypodermis) (Opens a modal)
• Where do our nails and hair come from? (Opens a modal)
• What's in sweat? (Holocrine, Apocrine, Merocrine Glands) (Opens a modal)
• LeBron Asks: Why does sweating cool you down? (Opens a modal)
• Overview of Sensation and Meissner's Corpuscle (Opens a modal)
• Pacinian's Corpuscle and Merkel's Disk (Opens a modal)
• Ruffini's Ending and Hair Follicle Receptor (Opens a modal)
• Pain and temperature (Opens a modal)
• Thermoregulation mechanisms (Opens a modal)

Lymphatic system introduction

• Why we need a lymphatic system (Opens a modal)
• How lymphatic vessels move fluid (Opens a modal)
• The lymphatic system's role in immunity (Opens a modal)
• Lipid and protein transport in the lymphatic system (Opens a modal)
• What is actually in lymph (Opens a modal)

218 Anatomy & Physiology Topics to Research

• Icon Calendar 18 May 2024
• Icon Page 1982 words
• Icon Clock 9 min read

Anatomy and physiology research topics delve into the detailed exploration and explanation of the structure and function of biological systems. They include studies on cellular processes, tissue structures, organ functions, and system interactions in various life forms. Key themes encompass neurophysiology, cardiovascular dynamics, endocrinology, musculoskeletal anatomy, respiratory physiology, and digestive mechanisms. Advanced subjects include genetic influences on anatomy, the impact of disease and aging on physiological function, and the role of modern imaging techniques in anatomical research. The research also focuses on comparative and evolutionary aspects of anatomy and physiology, opening new frontiers in understanding life processes. Hence, anatomy and physiology research topics enhance human health and animal welfare, contributing to biological knowledge.

Best Anatomy and Physiology Research Topics

• Exploring the Biological Clock: Impact on Human Behavior and Health
• The Mysteries of Human Memory: A Neurophysiological Approach
• Roles of Microglia in Neurodegenerative Diseases
• Physiology of Aging: Unveiling the Cellular Mechanisms
• Effects of Physical Exercise on Cardiovascular Health
• Science Behind Muscle Hypertrophy: Physiology and Adaptation
• Interlinkages between Gut Microbiota and Human Health
• Nutrition and Digestive System: Impact on Overall Health
• The Incredible Journey of Red Blood Cells in the Human Body
• Unveiling the Secrets of the Human Brain: Neuroanatomy Insights
• Skeletal System Disorders: Causes, Implications, and Treatment
• Investigating the Interplay Between Hormones and Human Emotions
• Impacts of Chronic Stress on Physical Health
• Mitochondrial Dysfunction and Its Role in Metabolic Disorders
• Endocrine System and Homeostasis: An Essential Balance
• The Human Eye: Unraveling the Complexity of Vision Mechanisms
• Unpacking the Biochemistry of Human Metabolism
• Intricate Design of the Human Nervous System: An In-Depth Study
• Respiratory System: Understanding Its Efficiency and Limitations
• The Complex Dynamics of the Renal System and Electrolyte Balance
• Human Reproductive System: A Focus on Fertility Issues
• Roles of Autophagy in Cellular Health and Disease
• The Biomechanics of Human Movement: A Detailed Analysis
• Skin: The Body’s Protective Barrier and Its Roles

Easy Anatomy and Physiology Research Topics

• Physiology of Pain: Perception, Pathways, and Management
• Investigation into the Lymphatic System: The Body’s Silent Guardian
• Maternal-Fetal Exchange: Exploring the Placenta’s Role
• Effects of Space Travel on Human Anatomy and Physiology
• Alcohol and Its Impact on Liver Function: A Detailed Examination
• Vascular System Adaptation during Exercise: An In-Depth Analysis
• Tackling Obesity: Unraveling the Role of Leptin and Ghrelin
• Analyzing the Physiology of High Altitude Adaptation
• Understanding the Biochemistry of Hair and Nail Growth
• Exploring the Endocannabinoid System and Its Physiological Roles
• How Does the Body Respond to Hypoxia?
• The Human Ear: Deep Dive Into the Mechanism of Hearing
• A Comprehensive Analysis of Human Reflexes and Reaction Times
• Telomeres and Aging: Unraveling the Connection
• Exploring the Function of Astrocytes in the Central Nervous System
• The Physiological Impact of Meditation on the Human Body
• Oxytocin: Its Role in Bonding, Birth, and Beyond
• Functions and Disorders of the Pituitary Gland: An Overview
• Study on the Neurobiology of Addiction
• Understanding Somatic vs. Germ-Line Mutations: Implications for Human Health

Interesting Anatomy and Physiology Research Topics

• Nitric Oxide in the Body: A Potent Messenger Molecule
• Insights Into the Physiology of Human Growth and Development
• The Sympathetic and Parasympathetic Nervous Systems: A Comparative Study
• Roles of Adipose Tissue Beyond Energy Storage: A Detailed Review
• Unraveling the Complexities of the Human Vocal Apparatus
• Investigating the Role of Antioxidants in Cellular Health
• Delving Into the Intricacies of Bone Remodeling
• The Influence of Temperature on Human Physiology
• The Role of Probiotics in Gut Health: An Exploration
• Hemostasis and Thrombosis: Understanding the Delicate Balance
• A Look Into the Biological Mechanisms of Fever Response
• Human Microbiome: Understanding Its Impact on Health and Disease
• Physiology of Human Hydration and Dehydration
• Dissecting the Biochemical Pathways of Drug Metabolism
• Anatomy of the Human Foot: Exploring Its Complex Structure
• Implications of the HPA Axis Dysregulation in Stress-Related Disorders
• Unfolding the Mysterious Mechanisms of Wound Healing
• Analyzing the Intricacies of the Blood-Brain Barrier
• Genetic and Environmental Influence on Human Anatomy and Physiology
• Delving Into the Mysteries of Human Taste and Smell
• Decoding the Human Genetic Code: Implications for Health and Disease

Anatomy Research Topics for High School

• Exploring the Neurological Basis of Human Memory
• Significance of Blood Types and Transfusion Compatibility
• Roles of the Endocrine System in Human Mood Regulation
• Anatomical Differences and Similarities Between Primates and Humans
• Heart’s Electrophysiology: Understanding the Cardiac Cycle
• Evolution and Function of the Human Vestigial Structures
• The Effect of Exercise on Lung Capacity
• Effects of Aging on Bone Density and Strength
• Sleep’s Impact on Cognitive Function: A Neurological Analysis
• Autonomic Nervous System and Its Role in Body’s Homeostasis
• Examining the Mechanisms of Pain Perception
• Lymphatic System’s Functionality in Immune Response
• Understanding the Digestive System: From Ingestion to Excretion
• Roles of Hormones in Adolescent Body Changes
• Detailed Analysis of the Human Olfactory System
• Human Skin: More Than Just a Covering
• Photoreception in Humans: Decoding the Visual System
• Muscle Fiber Types: Their Role in Exercise and Movement
• Genetics and Human Eye Color Variation
• Cellular Process of Wound Healing: A Comprehensive Review

Physiology Research Topics for High School

• Importance of the Circadian Rhythm in Health and Disease
• Relationship Between Diet, Metabolism, and Body Weight
• Roles of ATP in Energy Transfer Within Cells
• Function and Structure of the Human Ear
• Cardiovascular System’s Role in Maintaining Homeostasis
• The Genetic Basis of Inherited Metabolic Disorders
• Analyzing the Structure of the Human Spinal Cord
• Decoding the Function of the Hypothalamus in Hormone Regulation
• Evolutionary Significance of Bipedalism in Humans
• Interactions Between the Nervous and Muscular Systems
• Roles of Neurons in Transmitting Signals Across the Body
• Links Between Hydration and Kidney Function
• Understanding the Biological Clock and Its Impact on Sleep
• Mechanisms of Human Growth and Development
• Influence of Stress on the Human Immune System
• Examining the Complexity of the Human Hand’s Anatomy
• Investigating the Biological Processes of Aging
• Roles of Blood in Nutrient and Oxygen Transport
• Anatomy of the Human Eye and Vision Disorders
• Functions and Disorders of the Human Immune System
• Understanding the Body’s Electrolyte Balance and Its Importance

Anatomy Research Topics for College Students

• Exploring the Complexities of the Human Immune System
• Decoding the Structure and Function of the Human Brain
• Assessing the Physiological Impact of Stress on the Cardiovascular System
• Roles of DNA and RNA in Cell Division and Growth
• Chronic Diseases: The Impact on Organ Functioning and Structure
• The Role of Gut Microbiota in Digestion and Overall Health
• Understanding the Reproductive System: An In-Depth Study on Fertility
• Importance of Nutrition in Muscle Growth and Regeneration
• Neurobiology of Sleep: Examining Circadian Rhythms and Sleep Disorders
• Exercise Physiology: Impact of Physical Activity on the Human Body
• Sensory Systems: Unraveling the Mechanics of Perception and Response
• Roles of the Endocrine System in Homeostasis and Stress Response
• Anatomy of Aging: Physical and Physiological Changes in Elderly Individuals
• Regenerative Capabilities of Different Tissue Types in the Human Body
• Mapping the Human Genome: Implications for Disease Susceptibility
• Human Metabolism: Understanding Energy Production and Consumption
• Molecular Mechanisms in Cancer Development and Progression
• Intricacies of Wound Healing: A Cellular and Molecular Perspective
• How Does the Respiratory System Respond to High Altitude Conditions?
• Obesity: Effects on the Cardiovascular and Digestive Systems
• Uncovering the Secrets of the Human Microbiome
• Bone Density and Osteoporosis: A Closer Look at Bone Physiology
• Hematopoiesis Process: Understanding Blood Cell Formation and Maturation
• Neurotransmitters and Their Role in Human Behavior and Emotions
• Lymphatic System: Understanding Its Role in Immunity and Disease

Physiology Research Topics for College Students

• Thermoregulation in the Human Body: A Detailed Examination
• Physiology of Vision: How Does the Eye Interpret Light and Color?
• Roles of Hormones in Human Growth and Development
• Functions and Disorders of the Nervous System
• Prenatal Development: Tracing the Journey From Fertilization to Birth
• Roles of Neurons in Memory Formation and Retrieval
• Physiology of Pain: Understanding Pain Perception and Response
• Genetic Disorders: Impact on Organ Functioning and Anatomy
• Influence of Diet on Gut Health and Digestion
• Study of the Skin: Anatomy, Function, and Related Disorders
• Exploration of the Role of Stem Cells in Tissue Regeneration
• Roles of Proteins in Cell Structure and Function
• Mitochondrial Function and Dysfunction: Implications for Health and Disease
• The Human Heart: Anatomical Structure and Physiological Function
• Physiology of Fear and Anxiety: A Neurological Examination
• Respiratory Physiology: Gas Exchange and Breathing Mechanics
• Pathophysiology of Diabetes: An In-Depth Study
• The Liver: Understanding Its Functions and Related Diseases
• Understanding the Genetics of Human Height
• Vestibular System: Examining Balance and Spatial Orientation
• Roles of Glial Cells in the Human Nervous System
• Study of Connective Tissue: Structure, Function, and Disorders
• The Impact of Dehydration on Human Physiological Function
• Investigating the Causes and Consequences of Inflammation in the Body

Anatomy Research Topics for University Students

• Exploring the Biochemical Processes of Digestion in Humans
• The Physiological Impacts of Long-Term Space Travel on the Human Body
• Unraveling the Mystery of Human Memory: Anatomical and Physiological Aspects
• Examining the Role of Circadian Rhythms in Human Physiology
• Human Cardiovascular System: A Detailed Examination of Heart Functions
• Implications of the Human Nervous System on Cognitive and Sensory Functions
• Researching the Influence of Hormones on Behavior and Mood
• Effects of Aging on Muscular Strength and Bone Density
• Mitochondrial Dysfunction and Its Role in Degenerative Diseases
• Understanding the Physiology of Pain: The Role of Nociceptors
• How Neurons Communicate: An Investigation Into Synaptic Transmission
• Lymphatic System and Its Crucial Role in Immunity
• Comparative Study on Human and Animal Respiratory Systems
• Relationship Between Physical Activity and Metabolic Rate: A Physiological Perspective
• Cellular Regeneration: An In-Depth Look Into Stem Cell Biology
• Physiological Adaptations in Animals Living in Extreme Environments
• Sensory System of Insects: A Comparative Study to Human Physiology
• Autonomic Nervous System: The Interface Between Emotional States and Physiology
• The Complexity of the Endocrine System: A Focus on Hormonal Regulation
• Functions and Mechanisms of the Human Reproductive System

Physiology Research Topics for University Students

• Roles of Glial Cells in Neurological Health and Disease
• Importance of pH Balance in the Human Body and Its Regulation
• Genetic Disorders and Their Impact on Human Anatomy and Physiology
• Renal Physiology: A Comprehensive Study of Kidney Functions
• Mechanisms of Thermoregulation in Homeothermic Animals
• Unveiling the Intricacies of the Human Visual System
• How Does the Auditory System Decode Sound Waves Into Information?
• Physiology of Taste: Understanding the Mechanisms of Flavor Perception
• Examining the Physiological Responses to Hypoxia
• Skeletal System: An Investigation Into Bone Growth and Development
• The Role of the Liver in Metabolism and Detoxification
• Unpacking the Physiological Impacts of Chronic Stress on the Body
• Impacts of Nutrition on Human Growth and Development
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Anatomy & Physiology Project Ideas

• Exploring the Biological Clock: Understanding Circadian Rhythms
• Human Brain Plasticity: Neurogenesis and Learning
• Lung Capacity Differences: Factors Influencing Breathing Volume
• Investigating the Blood-Brain Barrier: Nature’s Biochemical Shield
• Unlocking Autophagy: The Body’s Recycling System
• Muscles and Movements: Kinetics of Human Motion
• Impacts of Nutrition on Bone Health: A Calcium Study
• Mystery of Sleep: Impact of REM and Non-REM Stages
• Cardiovascular Fitness: Exploring Heart Rate and Exercise
• Digestive System Efficiency: The Science Behind Metabolism
• Pain Perception: Understanding Neural Pathways
• Vision Variations: How Does Light Affect Sight?
• Studying Skin: The Human Body’s Largest Organ
• Hormones and Emotions: Impact on Human Behavior
• Lymphatic System: Body’s Silent Defender Against Diseases
• Roles of Enzymes: Catalysts in Digestion
• Fascinating Nervous System: Synapses and Signaling
• Human Microbiome: Impact on Health and Disease
• Taste and Smell: Exploring Sensory Perception
• Aging and Physiology: Changes in Organ Function Over Time
• Power of Regeneration: Comparative Study Between Species
• Endocrine System: The Influence of Hormones on Growth and Development

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222 Best Anatomy Research Paper Topics To Discuss

Human anatomy and physiology are undoubtedly among the most complex areas of study. This is a field that is ever-growing in terms of new discoveries, changes, and understanding of certain processes. Needless to say, the scope for research is high with these subjects as well. If you are a student of medicine, genetics, or any other field of study that is related to the human body, chances are that you will have to present an interesting human anatomy essay as part of your course.

Given the complex nature of the subject, it is hard to narrow down on topics that give you enough information without becoming too overwhelming. Whether you are looking for research paper topics or anatomy and physiology project ideas, here are over 200 topics that will help you write a crisp, concise, yet informative paper for the best grades.

Simple Anatomy and Physiology Research Paper Topics

These anatomy and physiology topics for research papers will help you get the best ideas to write a detailed paper.

• The role of the cell structure in studying human anatomy
• Detailed investigation of the human body cavity
• The primary systems of the human body
• Scientific evolution and the changes in the understanding of human anatomy and physiology
• Why is Andreas Vesalius known as the father of human anatomy?
• The first-ever dissection of the human body and the aftermath
• The effects of dehydration on human metabolism
• The in and outs of the human digestive system
• The complex network of the human cardiovascular system
• The harmful effects of toxic chemicals on the health of humans
• The evolutionary history of the nervous system
• The evolutionary history of the human brain
• Physiology of the reproductive system
• Mitochondria and why it is called the powerhouse of the cell
• Functional architecture of the human skeletal system
• The cerebellar artery and its relationship with cerebellomedullary fissure
• Causes for degenerative rotator cuff tear
• Treatment of hepatic veins
• Chemical messengers in the human body
• 5 methods of maintaining homeostasis in the human body
• The evolutionary history of the appendix
• The mechanism of hearing
• Instances of extreme temperature sustenance by the human body
• Changes in the human body with age
• The role of the internal body temperature
• Physics of the human skeletal system
• The different enzymes in the human body and their roles
• The role of iron in the human body
• Parts of the human body that continue to grow with age
• The human body is an open system. Comment on this statement.

Top Anatomy Research Topics

These are some popular anatomy research paper topics that have been used by students successfully. These topics allow you to collect ample data and present interesting papers that can help you get better grades:

• Components of the human body
• Why is the human body unable to digest sucralose
• The design of the body that allows it to conduct electricity
• The role of the endocrine system in metabolism.
• The advantage of the human body being maintained at a constant temperature of 37 degrees
• What is the reason for the human body being made of water mostly?
• The difference between the body composition of men and women
• Compare the nucleus of the cell to the brain
• The microbiota of the human body
• Provide examples of absorption in the human body
• The meninges around the brain and their role in the human body.
• The purpose of the Schwann cells in the human body
• Describe the structure of the DNA molecule and its evolutionary history
• Physiology and how it is affected by exercise
• The primary differences between physiology and pathophysiology
• Negative feedback and its physiology
• What does systemic physiology mean?
• The importance of physiology in modern medicine
• What is the difference between physiology and anatomy
• The evolution of human neurobiology
• Ceruminous glands and their purpose in the human body
• Describe the major branches of physiology.
• Difference between environmental, evolutionary, cellular and developmental physiology
• The evolution of Kinesiology and how is it different from physiology
• Different planes of the human body
• The division of the human body into systems
• Compare the adrenal body in frogs and adrenal glands in the human body
• How do physiology and anatomy complement each other?
• What are the principles of physics that are studied in physiology
• The importance of osmosis in the human body
• The composition of the matrix of the bone.
• History and discovery of the human anatomy
• Studying the anatomy of other species helps understand human anatomy better. Provide examples to prove this statement.
• The relationship between healthcare, anatomy, and science.
• Changes in the human anatomy during pregnancy
• Explain the proximal and distal parts of the human body with reference to one organ.
• Write a paper on the study of abnormal anatomy
• What are buffers? And the need for buffers in the body
• Explain the process by which the human body obtains energy from food.
• What are the basic things that the body needs in order to survive?
• The role of silicon in the human body
• Examples of the resilience of the human body
• The effects of cortisol in the body
• Does stress change the physiology and anatomy of the human body?

Topics For a Great Human Anatomy Research Paper

Here is a list of anatomy paper topics that open up several questions as you research in-depth about them. This allows you to write a paper that is detailed and full of interesting information to keep the reader engaged.

• Is the DNA the same in each cell of the human body? Provide examples to prove this statement.
• The human body is not an intelligent design. Support or argue against this statement with examples
• The different receptors in the human body and their roles
• The structure of different types of muscles in the human body and the function of each type of muscle.
• The process of active transport and its importance to the survival of a cell.
• The human anatomical position and its significance.
• Physiology is a life science. Write in detail about this statement
• How does the study of anatomy cross over with the arts?
• 100 most interesting facts about the human body
• Foods that the human body cannot digest. Explain this with reference to physiology and anatomy
• The importance of maintaining pH within a given range in the human body
• The physiological and anatomical changes that occur in the body after death.
• The major role of the RNA in the human body
• Write a paper on the communication system within the human body and how it is so efficient.
• Provide a detailed analysis of the body systems affected by schizophrenia
• Provide a detailed analysis of the body systems affected by meningitis
• Why is it important to study physiology and anatomy to understand psychology better?
• Name the body systems responsible for the reflex action and explain the process in detail.
• Write a paper on the human immune system and its functions
• What are some “useless” organs or parts of the human body?
• The role of sugar in the human body
• Are there any internal organs that are cold? If so, why?
• The two systems responsible for coordinating various body functions and the systems that regulate them.
• The physiological and anatomical changes in the body during adolescence.
• The role of carbon dioxide in the human body
• A detailed note on the 10 major muscles in the human body
• The anatomical and physiological changes in the body of a heroin addict
• What is the role of water in the human body?
• The need for sodium in the human body
• Explain the physical act of shivering from a physiological point of view
• The role of the kidneys in maintaining an acid-base balance
• Explain the anatomy of the human reproductive system and its evolutionary significance.
• What are some similarities between the male and female reproductive systems?
• Is the female reproductive system more complex than the male reproductive system? Explain with examples
• The anatomical and physiological changes that take place at puberty
• The effect of zinc on the human reproductive system.

Interesting Anatomy Topics For College Essay

Human anatomy and physiology are extremely interesting in general. There are some specific subjects that are particularly interesting. Here is a list of some of these anatomy and physiology research paper topics that are ideal for your next assignment.

• What are the environmental factors that affect the human reproductive system?
• The five hormones of the female reproductive system and their significance.
• The effect of oral contraceptives on the physiology of the female reproductive system
• The function of the female fallopian tubes and their evolutionary history
• Common diseases of the human reproductive system
• Discuss in detail the design of the sperm and its function in fertilizing the egg.
• The importance of pH in the human reproductive system.
• The four secondary sexual characters of females
• A detailed anatomical perspective of sexual reproduction in humans.
• The base pairs in the DNA molecule contain nitrogen.
• The detailed functions of the human skeletal system
• Evolutionary study of the human skull
• The role of the human skeletal system in the production of blood
• The differences between tendons, ligaments, and cartilages with examples of their function and structure
• The physiology of a fracture and how it heals over time
• The cartilaginous joints of the human body and how they are different from other joints.
• The role of the synovial fluid in the joints and how the body maintains the levels consistently.
• The five primary options to keep the skeletal system healthy
• The major components of the skeletal system besides the bones.
• The 3 major functions of the muscular system and how it is designed to carry out these functions?
• The relationship between the skeletal system, muscular system, and the nervous system
• Common degenerative disorders of the human skeletal system
• How calcium plays an important role in the human skeletal system.
• The common infectious diseases of the skeletal system
• The anatomical differences between the muscular structure of different races
• Are there any major anatomical differences between the structure of the brain of people from different ethnicities?
• The effect of obesity on the skeletal system
• Common lifestyle issues that affect the muscular and skeletal system
• What are the anatomical and physiological implications of poor posture?
• The cranial bones and their evolutionary history.
• The anatomical details of human blood.
• The physiology of the production of blood cells in the human body.
• Changes in the structure of the bones after pregnancy.
• Anatomical changes in the human muscular system as a result of weight training.
• Anatomical changes in the human muscular system as a result of the cardiovascular system
• A detailed study of the evolution of the human vertebral column.
• The changes in the human skeletal and muscular system from infancy to adulthood.
• The relationship between tendons, muscles, and bones.
• Relationship between the respiratory system, circulatory system, and the muscular system
• An anatomical comparison of the male and female muscular systems.
• The common types of muscle contractions with examples.
• Myosin and its significance to the human muscular system
• The importance of smooth muscles in the human body
• The physiology of the movement of food in the esophagus and the different movements of the muscles during the process.
• The process of muscle atrophy
• How do involuntary muscles function? Explain in detail.
• The effect of the muscular system on the other systems of the human body.
• How do neurotransmitters in the body function? Explain with examples of the most common neurotransmitters in the body.
• Technological development and how it helps in repairing damaged muscles
• The role of protein in the structure and development of the human muscles
• The anatomy of the human eye and its unique features
• The physiology of human vision
• The physiology of adaptation of vision in the dark.
• The physiology of cataracts.
• The function and unique features of the optical nerves
• What are the features of the retina that make it possible for us to see
• Difference between aerobic and anaerobic movement and its impact on the muscular system.
• The physiology of the production and storage of energy in the cells.
• The physiological changes that occur as a result of vitamin deficiency. Choose one type of vitamin to provide details.
• The role of the integumentary system in the human body
• The relationship between the immune system and the integumentary system.
• Examples of genetic disorders of the integumentary system.
• How does the integumentary system prevent dehydration of the body?
• The layers of the skin and their protective function.
• The evolutionary advantage offered by fingerprints
• The process of keratinization and its importance
• The anatomical function of tears
• How is the human hair formed?
• The body systems that are affected by acne.

Anatomy Project Ideas For College

An important anatomy project coming up? Here is a list of project topics in human anatomy that are perfect for developing a college project that is interesting and informative at the same time.

• Explain body odor from a physiological point of view.
• The synthesis of vitamin B in the skin.
• The role of the sweat glands in maintaining the body temperature.
• The six principal functions of the human integumentary system.
• The effect of a burn on other parts of the body besides the skin.
• The process of eliminating waste from the body and the physiological changes that take place.
• The types of glands in the human body.
• The skin is an organ. Explain with examples
• The body systems are engaged when you are swimming.
• A detailed understanding of the formation of the epidermis
• How does the human skin stay waterproof? Why is this significant?
• The response of the body to trauma or a wound. Provide step-by-step details.
• The importance of inflammatory response
• The physiology of common allergies
• The function of anti-inflammatory medication and how it works on the human body
• The role of antibiotics in inflammatory response
• The physiology of the immune response of the human body.
• The physiology of cancer
• What is an auto-immune disease? How is the body affected by it?
• The anatomical and physiological changes as a result of AIDS.
• The production and function of the human growth hormone
• The physiological significance of the human thyroid gland
• Common issues of the thyroid gland and the physiological changes.
• The role of alcohol and inflammation in the body
• The changes in the brain as a result of consumption of narcotics
• The meaning of histamine and what does it do to the body?
• The function of the human lungs with respect to the circulatory system
• The exchange of various gases between the body tissues and the lungs.
• The role of the lungs in maintaining homeostasis in the human body
• The physiological repercussions of pneumonia
• Quadriplegia and the ability of involuntary muscle function.
• The role of squamous epithelial cells in the human lungs.
• The development of scar tissues and why it is important.
• The anatomical significance of the alveoli of the lungs
• Physiological changes that lead to asthma
• How does the novel coronavirus affect the physiology of the human body?
• Interactions between the cardiovascular system and the respiratory system.
• The process of delivery of oxygen by the circulatory system.
• The role of visceral fat in the body
• The physiology of fat metabolism
• A detailed understanding of the autonomic nervous system and its evolutionary significance
• Examples of evolutionary changes in human anatomy.

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Human Physiology

Sep 04, 2014

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Human Physiology. Zou Yuan, PhD Department of Physiology Dalian Medical University. What is Physiology?. A branch of biological science. To study normal functions of organs and organ systems of the body. What will be learn in Physiology. Physiological function of organs.

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• energy metabolism
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Presentation Transcript

Human Physiology Zou Yuan, PhD Department of Physiology Dalian Medical University

What is Physiology? • A branch of biological science. • To study normal functions of organs and organ systems of the body.

What will be learn in Physiology • Physiological function of organs

Cell and its Function

Blood Circulation Blood

Respiration Digestion and Absorption

Energy Metabolism and Body temperature Regulation

Kidney The Nervous System

Endocrine System

Two themes of Physiology • Homeostasis • Integration

Developmental History of Physiology William Harvey(1578-1657) An english physician who, by observing the heart in small animals and fishes, proved experimentally that heart receives and expels blood during each cycle, found valves in the veins and the flow of blood in one direction. He developed the first complete theory of the circulation of blood. He published his observations and interpretations in Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus (1628), often abbreviatedDe Motu Cordis.

W. Beaumont (1785-1853) American frontier doctor who treated Alexis Saint Martin, a nineteen-year-old Canadian trapper accidentally wounded in the stomach. When the wound healed, Beaumont observed that a hole remained in the stomach cavity. He used the opportunity to insert and withdraw various foods after varying periods of time and tabulate the results. Pavlov, Ivan Petrovich (1849-1936) Russian physiologist. He received the Nobel prize in medicine and physiology in 1904. stomach secretion and nervous regulation.

Neural Science

1993, Glasgow, Integrative Physiology At present, from gene to function. We can see, the research levels from whole body, to organs, tissues, cells, organelles, and genes.

Methodology • Physiology is a experimental science. • In vivo: perform on the whole animals. • In vitro: perform on isolated tissue or organ. • Acute: perform on the animals under anesthesia. • Chronic: perform on conscious animals for a long time.

Application and significance • Medicine • Need for know ourselves • Need for practice • Plant Physiology, Animal Physiology, and so forth. • Diving Physiology, Aviatic Physiology.

Fundamental Characteristics of Living Organism • Metabolism • Excitability • Reproduction or adaptation

Metabolism: • Catabolism: catabolic reaction, decomposition. • Anabolism: anabolic reaction, synthesis of molecules. • Material metabolism: learned in Biochemistry. • Energy metabolism: will be learned in Physiology.

Excitability: • Definition: A ability of response to environmental stimuli. • Stimulus: changes in external or internal environment. • Physical stimulus: thermal electric phonic photic

Chemical stimulus: • Biological stimulus: chemical substances bacteria, virus

Response: • Excitatory response: excitation • Inhibitory response: inhibition • Essence of excitability: • AP production

Reproduction • A process by which an animal produces one or more individuals similar to itself. • Reproduction makes species succession possibility.

Regulation of Body Functions • Nervous Regulation • Humoral or Neuro-humoral Regulation • Auto-Regulation

Homeostasis • Internal environment: • Cells to live, namely extracellular fluid. • Interstitial fluid, plasma, etc. • Physical and chemical status are stable: T, pH, etc. • Homeostasis: W.B. Cannon • Constant condition of internal environment. • A dynamic equilibrium: CellTissueOrganSystem. • Homeostasis needs regulatory mechanisms.

Nervous Regulation • It is completed under CNS by reflex that the regular response was made to internal or external stimuli under CNS. • Reflex arc: • Sensor, afferent and efferent limbs, reflex center, and effector. • Classification: • Unconditional reflex: congenitally available • Conditional reflex: learned by individual life. • Properties: • Accuracy: reflex arc is stereotyped. • Rapidity: speed of AP

Hormonal or Neuro-hormonal Regulation • It is completed by special chemicals or metabolic products. • Regulative types: • Endocrine: • Paracrine: • Neuro-endocrine: • Properties: • Slow in onset, diffuse in nature, longer in duration.

Auto-regulation • It is completed by a tissue or organ itself, neither on nervous nor humoral control. • Properties: • Local in range • Limited in action

Feedback Control of body function • Feedback: • To feed the output information back to the control so as to modify the nature of control. Physiological information Control element Effector Feedback information

Forms of feed back: • Positive Feedback: • Negative Feedback: • Feed-forward control:

Contents • Chapter 1 Introduction • Chapter 2 The Cell and its Function • Chapter 3 Blood and Body Fluid • Chapter 4 The Heart and Circulatory system • Chapter 5 Respiration • Chapter 6 Digestion and Absorption • Chapter 7 Energy Metabolism and Body temperature Regulation • Chapter 9 The Kidney • Chapter 10 The Nervous System • Chapter 11 The Endocrine system

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Human Eye Physiology. Václav Hlaváč. Plato , 427-347 B.C. inner fire in the eye + emanated ray Epicurus , 341-270 B.C., replicas of the object into the mind Galen , 130-200, physiological details, rays out and in. Alhazen , Arabic philospopher, 965-1040, idea of pinhole camera

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Painless Pursuits: Uniting Regional Experts in Pain Research

A new forum brings together scientists and students to forge research collaborations within the pain research community throughout St. Louis and the Midwest. 

Placing any discipline’s greatest minds in the same room for a forum is not an easy feat. It requires planning, connections, and space for all to converge and share their ideas. Throughout the world, thousands of pain researchers attend international and national conferences, symposiums, and meetings to share their insights and connect with others in the field. But, it is easy to get lost in the shuffle of such big events and never fully appreciate the research that might be happening just a few miles from your own lab.

This challenge became an opportunity, according to Daniela Salvemini, Ph.D. , William Beaumont Professor and chair of the Department of Pharmacology and Physiology and director of the Institute for Translational Neuroscience (ITN) . Salvemini said she noticed the need for a meeting of neuroscientists studying the ubiquitous phenomenon of pain centered on the St. Louis region in order to form collaborations, focus on the region’s centers of expertise, and increase the rate of pain research throughout the Midwest.

In September 2023, ITN launched the inaugural Saint Louis Translational Pain Research Forum (STL-TPRF), in collaboration with the Washington University Pain Center and the Center for Clinical Pharmacology. The goal for Salvemini and her co-organizers, Robert Gereau IV, Ph.D., vice chair for research at Washington University in St. Louis and director of the Washington University Pain Center, and Amynah Pradhan, Ph.D., director for clinical pharmacology and assistant professor at Washington University in St. Louis and the University of Health Sciences and Pharmacy, was to unify pain researchers from the St. Louis region under one roof. Yet, the vision for the forum extended far beyond physically getting people into the same room. Salvemini said that through the forum, which was attended by more than 100 researchers and students, she hoped to inspire the next generation of skilled pain researchers.

“We are educating the next generation of researchers, clinicians, and educators in basic neuroscience, and we want to provide as many opportunities as we can,” she said.

An Idea Shifts Into Reality

When Salvemini began brainstorming ideas for a scientific forum in St. Louis, she knew she wanted to set up an event that would specifically discuss matters related to translational pain research. In December 2022, she got the ball rolling by initiating conversations with Gereau and Pradhan. These first discussions laid the foundation that would form the first STL-TPRF on Sept. 22–23, 2023, hosted at the University of Health Sciences and Pharmacy campus.

“I wanted this to be based in St. Louis to showcase the great work of researchers from different universities in St. Louis that are doing translational pain research and broaden it to bring in other researchers from more institutions within the Midwest,” Salvemini said.

“The forum would showcase the research around pain that we do and provide the opportunity to increase collaborations among researchers," Salvemini said.

As the idea for the forum took hold, Salvemini, Gereau, Pradhan, and their teams immediately went to work executing a plan for a two-day event that would unite leaders in the field of pain research, facilitate the exchange of industry insights, and explore novel approaches to tackle the complex topic of pain management and treatment. But Salvemini knew they needed to act quickly to make it a success. Through their combined efforts and the organization and dedication of their assistants, Emily Helm of SLU and Emma Witzke of Washington University in St. Louis, they were able to pull the forum together in a matter of months.

“We started the [planning] in January 2023 so organizing everything to be ready in September was a big challenge,” Salvemini said. “But, it was amazing how this symposium went. We had 170 people that registered and 170 people that attended.”

Two Full Days of Success

Unifying the brightest minds in pain research requires many phone calls, email communications and online marketing efforts. The STL-TPRF team secured two renowned pain researchers to provide a national perspective on the field.

Walter Koroshetz, M.D., director of the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NIH - NINDS), served as the keynote speaker, and Vivianne L. Tawfik, M.D., Ph.D., associate professor at Stanford University, led talks that energized the audience and lent credibility to the event and to the St. Louis region’s position on the pain research map. The STL-TPRF also invited speakers from all three partner institutions as well as other researchers from NIH - NINDS, Northwestern University, Indiana University Bloomington and the University of Minnesota.  

Salvemini remarked that having all those speakers present at the forum put St. Louis and SLU’s Institute for Translational Neuroscience up at the forefront of this research, and it helps achieve SLU’s overriding mission of increased “research growth within the University.”

“The forum is providing these hubs and the ability to say this is what we are doing in terms of translational research, and it's very powerful,” she said. “Our name counts and gives SLU this kind of prestige that helps increase research growth within the University, and bridges with other institutions like Washington University and the Center of Clinical Pharmacology.”

Highlighting SLU Researchers

The STL-TPRF invited a variety of scientists from across the Midwest and beyond to share their work in pain research. Two SLU researchers were among them.

Aubin Moutal, Ph.D., assistant professor of pharmacology and physiology at the SLU School of Medicine, studies rare autoimmune clinical conditions to identify novel proteins involved in chronic pain. He discussed his research on the painful symptoms of many autoimmune disorders and his discovery of a specific protein involved in autoimmune-driven pain.

Christopher Arnatt, Ph.D. , associate professor of pharmacology and physiology and SLU’s Department of Chemistry, has been involved in drug discovery, and his lab focuses on the design, synthesis, and initial evaluation of drug candidates. In his presentation, Arnatt discussed the arm of his research that focuses on the role of a cellular receptor, called GPR138, which sits on the surface of some immune cells and plays a key role in driving inflammation. This protein is integral to the development of neuropathic pain in the human body, and Arnatt is now synthesizing compounds in his lab that specifically target the receptor to potentially block neuropathic pain.

Both Moutal and Arnatt said that the STL-TPRF was highly successful in showcasing current knowledge, sparking collaborations, and stimulating new ideas in pain research.

“Even though we’re living in the same city, we don’t actually meet often,” Moutal said. “It was nice to have this so we could chat with all of the other [researchers] from the other universities, and that is how we start collaborations.”

Arnatt added this forum also could increase the community of researchers working on pain and produce more opportunities for students in and around St. Louis.

“There is a very active recruitment of people working on pain,” Arnatt said. “This meeting will benefit from staying local, but it will grow because the community is growing. We can also give a better platform for students, trainees, and postdocs to present their own work and shine within the community.”

Enriching Student Skills

Neuroscience has captured student interest at SLU since the late 2000s, when a dedicated group of students proposed the creation of a major in neuroscience. It became a formal interdisciplinary degree program in 2014. As interest in neuroscience grew, the institute began offering numerous research opportunities and events, including Neuro Day, which is ITN’s annual research symposium, and the STL-TPRF, for students in the neuroscience program and other degree programs.

“We provide a lot of opportunities for the undergraduate students that are in the undergraduate neuroscience program,” Salvemini said. “Undergraduates can join the labs of principal investigators (PIs) and be exposed to research and be trained in the research that we do in neuroscience and chronic pain.”

The STL-TPRF offered abundant opportunities for students and trainees to both hear from leading lights in the discipline and to showcase their own work in poster presentations during the forum. Students at SLU and other institutions presented 47 posters throughout the event and they displayed neuroscience and pain research findings in a variety of physiological contexts, including migraines, sickle cell pain, diabetes, and obesity-induced pain.  

Salvemini explained that giving students the space to present allows them to develop the skills they need to grow before entering their own careers in neuroscience.

“Trainee engagement is at the top of the list,” Salvemini said. “The more we do it, the more engagement we will have and the more of these types of activities and community outreach we will see. When people start taking initiatives, things will happen.”

Ambitions Ahead

As scientists engaged in pain research continue their work, Salvemini and her colleagues are readying for the second STL-TPRF, which is slated to take place in September 2025. Their ambitions for this next iteration are simple — to grow the forum and spread the word throughout the St. Louis region.

“We will definitely have it again in September 2025, and by then, we will have more time to prepare ourselves in terms of the distribution of information,” she said.

The STL-TPRF provides another level of training, information sharing, and community building that can only enliven the field of pain research. But its true impact lies in discoveries to come. Salvemini said she hopes this forum, now and in the future, contributes to successful growth within pain research and benefits the millions of people who are affected by chronic pain.

“Our goal is to help alleviate human suffering,” Salvemini said. “The education that we provide within these teams is all about training the next generation of scientists, educators, and clinicians who will hopefully continue our mission to help end human suffering through the understanding and discovery of novel treatments for pain.”

 Story by Mary Pogue, senior copywriter, Paradigm .

This piece was written for the 2023 SLU Research Institute Annual Impact Report. The Impact Report is printed each spring to celebrate the successes of our researchers from the previous year and share the story of SLU's rise as a preeminent research university. Design, photography, and some writing contributions are made by Paradigm . View the report.

Removing Bile Acid Receptor in Gut Blocks Intestinal Inflammation

August 15, 2024

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Mouse study could lead to ways to prevent disease

Rockville, Md. ( August 15, 2024 )— Removing a nuclear bile acid receptor that regulates glucose and lipid stability from the intestine blocked gut inflammation in mice, according to researchers at Children’s Hospital Los Angeles. The findings are published in the American Journal of Physiology-Gastrointestinal and Liver Physiology . The article has been chosen as an APS select article for August. 

The farnesoid (FXR) bile acid receptor plays a significant role in gut inflammation. This is the first documented case of FXR deletion protecting the intestinal barrier in multiple models of acute intestinal inflammation. Failure of the intestinal barrier has long been associated with body-wide infection (sepsis) that originates in the gut. Intestinal barrier protection is due to lowered inflammatory cells and maintenance of tight junctions linking the intestinal lining. When these cells do not stick together, intestinal contents leak into the abdominal cavity and other areas of the body, resulting in disease.

Gut inflammation can cause a number of health conditions, including ulcerative colitis and Crohn’s disease. The effects are wide-ranging and include:

• Stomach pain
• Weight loss
• Loss of appetite

In this study, physiologists measured the amount of inflammation in the intestine after FXR was removed. Then, they used advanced microscopy to see the molecules that link epithelial cells and observe how a lack of FXR affects the intestinal barrier in the presence of disease. The lack of this receptor kept the gut barrier intact and prevented the animals from becoming sick.

“Inflammatory diseases of the intestine are a hallmark of many pathologies, including inflammatory bowel disease and gut-origin sepsis,” said Christopher Gayer, MD, PhD, the study’s lead author and chief of pediatric surgery at Children’s Hospital Los Angeles. “The purpose of this research is to better understand the role of FXR within the intestinal epithelium which could help control and manipulate inflammation.”

Read the full article, “ FXR deletion attenuates intestinal barrier dysfunction in murine acute intestinal inflammation .” It is highlighted as one of this month’s “best of the best” as part of the American Physiological Society’s APS select program. Read all of this month’s selected research articles .

NOTE TO JOURNALISTS: To schedule an interview with a member of the research team, please contact APS Media Relations or call 301.634.7314. Find more research highlights in our Newsroom .

Physiology is a broad area of scientific inquiry that focuses on how molecules, cells, tissues and organs function in health and disease. The American Physiological Society connects a global, multidisciplinary community of more than 10,000 biomedical scientists and educators as part of its mission to advance scientific discovery, understand life and improve health. The Society drives collaboration and spotlights scientific discoveries through its 16 scholarly journals and programming that support researchers and educators in their work.

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• Short-chain Fatty Acids Reduce Inflammation in the Lungs of Older Mice
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• Women Lose More Muscle than Men in Spaceflight, Additional Sex-specific Research Needed
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EDITORIAL article

Editorial: highlights from the 12th plant growth-promoting rhizobacteria workshop.

• 1 Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea
• 2 Department of Biosystems and Bioengineering, Korea Research Institute of Bioscience and Biotechnology (KRIBB) School of Biotechnology, University of Science and Technology, Daejeon, Republic of Korea
• 3 Department of Cell and Developmental Biology, University of California, San Diego, San Diego, CA, United States
• 4 Department of Pediatrics, School of Medicine, University of California, San Diego, San Diego, CA, United States
• 5 Department of Biology, University of British Columbia (Okanagan), Kelowna, BC, Canada
• 6 The Bashan Institute of Science, Auburn, AL, United States
• 7 Department of Entomology and Plant Pathology, Auburn University, Auburn, AL, United States

Editorial on the Research Topic Highlights from the 12th plant growth-promoting rhizobacteria workshop

Introduction

The term ‘Plant Growth-Promoting Rhizobacteria (PGPR)’ was coined by Joseph W. Kloepper in 1978 ( Kloepper and Schroth, 1978 ). He defined PGPR as “Naturally-occurring, root-colonizing bacteria that benefit plants by growth promotion and biocontrol”. Nine years later, he organized the first international PGPR workshop at 1987 in Canada. Subsequently, the Workshop has been held in Switzerland (1990), Australia (1994), Japan (1997), Argentina (2000), India (2003), The Netherlands (2006), Oregon (2009), Colombia (2012), Belgium (2015), and Canada (2018). The International PGPR Workshop series is the most comprehensive conference in the field of PGPR/Plant Growth-Promoting Bacteria (PGPB). Professor Kloepper’s philosophy for the workshops was as a venue to bring together young and established researchers and industry to increase our understanding of the fundamental and applied aspects of PGPR via formal presentations and informal discussion to advance the field. The 12th PGPR Workshop was held in Toulouse, France, on May 29th - June 2nd, 2023. This Frontiers Research Topic aims to collect selected contributions from this PGPR Workshop. This Research Topic aims to bring together new findings and applications of PGPR.

Carrying the old knowledge gained into new fields

Since Professor Kloepper’s retirement, the chronicles of a representative PGPR strain were summarized by former students in his laboratory at Auburn University ( Jang et al. ). Out of many PGPR species, Bacillus spp. received much attention due to their ability to form endospores that are resistant to biotic and abiotic stresses such as limited nutrients, hydration, heat, and extreme pH. Bacillus velenzensis (formerly Bacillus subtilis and B. amyloliqufaciens ) strain GB03 was the first bacilli product developed by long-term collaboration with Professor Kloepper and Gustafson LLC, Plano Texas, USA. In this review, authors describe the process from isolation to commercialization as well as the mechanisms of plant growth promotion and biological control against soil-borne pathogens. The status of PGPR study in central Africa including Burundi, Rwanda, and the Democratic Republic of Congo was reported by Nihorimbere and colleagues ( Nihorimbere et al. ). PGPR provide a greater potential than chemical pesticides in the tropical region to manage the plant diseases occurring because the European Union banned 30% of the pesticides used in this region. The transfer of knowledge and know-how from scientists in global north countries needs to come through scientific collaboration.

Make plants healthier in the face of abiotic stresses

As we already recognized in 2023, the hottest year in human history reported by European Union’s Copernicus Climate Change Service ( https://www.ncei.noaa.gov/access/monitoring/monthly-report/global/202313 ), the crisis of climate change is upon us. Due to climate change, the cultivation of crop plants can be limited. To combat environmental stresses, we need silver bullets to overcome these constraints. Elicitation of induced systemic tolerance by PGPR can be a solution to abiotic stresses in plants ( Yang et al., 2009 ). Through biochemical and molecular evaluation, three bacterial strains isolated from tomato soil and roots were selected for plant responses under water stresses. The tomato’s physiological changes were characterized following treatment with PGPR ( Zampieri et al. ). Heavy metals can also suppress plant growth directly. A metal tolerant PGPR strain Paraburkholderia ultramafica STM0279 T elicited metal tolerance in a tropical hub plant Tetraria comosa ( Bourles et al. ). The experiments were conducted in New Caledonian ultramafic soil also known as serpentine soil containing high level of toxic metals, Ni, Co, Cr, and Mn and low levels of essential plant nutrients N, P, and K. T. comosa , belonging to the Cyperaccae family, is a pioneer and abundant herbaceous member in New Caledonian ultramafic soil. Abou Jaoude et al. gave a new insight into PGPR and their metabolite-induced changes to plant photosynthetic activity as a parameter of plant ecophysiology under non-stress and biotic and abiotic stress conditions through metanalyses of the topic-related references. Collectively, PGPR provide potential to protect plants from environmental stresses derived from climate change.

Protecting plants against unculturable pathogens

PGPR utilize plant protectants as biological control tools against foliar and soilborne pathogens. Due to the experimental difficulty of growing non-culturable pathogens, testing the biocontrol efficacy by PGPR was limited. Here, two new results with unculturable aboveground and belowground pathogens shed light on a new strategy to control non-culturable and economically important pathogens. First, the cell wall degrading enzyme LytD from B. subtills plays a pivotal role in biological control against grape downy mildew caused by Plasmopara viticola ( Wang et al. ). The loss of function of the autolysin N -acetylglucosaminidase LytD in B. subtills GLB191 disrupts biocontrol capacity, biofilm formation, and leaf colonization. The authors provide the first example of the role of bacterial autolysin in plant protection by PGPR. Secondly, a group of scientist in Colombia targeted the management of another non-culturable fungal pathogen Plasmodiopora barassicae , a causal factor of clubroot diseases in cruciferous plants. The PGPR consortium reduced the disease incidence up to 56% indicating an efficient and integrated disease management tool even in the highly P. barassicae -infested fields ( Moreno-Velandia et al. ).

Beyond growth promotion, improving plant metabolite and mineral contents

Tanney et al. demonstrated that application of Bacillus sp., Pseudomonas sp., and two bacterial combination treatments increased the cannabinoid contents of cannabis ( Cannabis sativa ). Cannabis has received increased attention recently, although heavy legalization limits its cultivation under greenhouse and field conditions. PGPR inoculation triggered trichome development and increased cannabinoid amount only under a low nutrient regime for six weeks ( Tanney et al. ). In addition to PGPR-mediated increase of plant secondary metabolites, it is also reported that mineral uptake into vegetables was promoted by B. subtilis inoculation ( Oliveira et al. ). B. subtilis inoculation increased Ca, Mg, S, K, and N in shoot and also enhanced photosynthesis, intracellular CO 2 contents, and water use efficiency. Guardado-Fierros et al. compared a classic indole-3- 202 acetic acid (IAA) quantification method, the Salkowski method to 203 ultra-performance liquid chromatography coupled with a Mass 204 Spectrometer (LC-MS/MS) using the supernatant culture of ten 205 PGPR strains. The Salkowski method overestimated the IAA concentration by a maximum of 1,042 fold without tryptophan and 16,330 fold with tryptophan due to the detection of other indole compounds. The demands for high quality and functional food are increasing worldwide. PGPR bring a great potential to induce beneficial plant secondary metabolite production or mineral uptake to meet consumer demand.

Unveiling genetic architecture of PGPB-triggered growth promotion

To date, plant genetic traits associated with PGPB-triggered plant growth promotion have not been widely assessed. The PGPB Pseudomonas siligins OTU6_ Psi _1 isolated from Arabidopsis thaliana leaf was examined in genome wide association studies by inoculating seed of 162 natural accessions from the southwest of France under in vitro conditions ( Ramirez-Sanchez et al. ). From intensive analysis, the polygenic genetic architecture underlying a strong negative trade-off was detected. Besides sole growth-related genes, dual functionality genes, SBT3.5 and JAZ11 for growth and defense were identified. The results will help breeding programs improve the capacity for PGPR-induced crop growth promotion, yield and quality.

This Research Topic covered recent data on the PGPR/PGPB-plant interactions. PGPR/PGPB are recognized as a potential silver bullet to reduce these detrimental side effects while sustainably enhancing crop production. The current studies pave a new way for next-generation PGPR applications. We are very positive about the future of PGPR-related fields. Strong collaboration between industry and academia and between global south and north is also required now. Finally, as was Professor Kloepper’s wish, we hope to inspire the next generation of researchers to inherit this field and to share new ideas to solve the impact of planetary problems such as climate change on agriculture.

Author contributions

C-MR: Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing. LN: Supervision, Writing – original draft, Writing – review & editing. LB: Writing – original draft, Writing – review & editing.

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was carried out with support from the Cooperative Research Program for Agriculture Science and Technology Development (Project No. RS-2022-RD010288) of the Rural Development Administration, Bio & Medical Technology Development Program of the National Research Foundation (NRF), funded by the Ministry of Science & ICT (NRF-2021M3A9I5021439), and the Korea Research Institute of Bioscience and Biotechnology (KRIBB) Initiative Program, Republic of Korea (for CMR).

Acknowledgments

We thank the enormous number of contributors who worked with strain GB03 from isolation to commercialization. We especially appreciate previous students, visiting scientists, and many collaborators in Joe Kloepper’s lab.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

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Keywords: PGPR, induced systemic resistance, induced systemic tolerance, microbiome, LMICs, PGPB

Citation: Ryu C-M, Nelson LM and de-Bashan L (2024) Editorial: Highlights from the 12th plant growth-promoting rhizobacteria workshop. Front. Plant Sci. 15:1470576. doi: 10.3389/fpls.2024.1470576

Received: 25 July 2024; Accepted: 05 August 2024; Published: 14 August 2024.

Edited and Reviewed by:

Copyright © 2024 Ryu, Nelson and de-Bashan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Choong-Min Ryu, [email protected]

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.